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[Diagnosis of unexplained syncope in children: a multi-center study].
Zhonghua Yi Xue Za Zhi. 2009 Jul 28; 89(28):1947-50.ZY

Abstract

OBJECTIVE

To examine the diagnostic value of head-up tilt test in children with unexplained syncope (UPS).

METHODS

A total of 379 children (171 males, 208 females) aged 3-18 years, mean age (12 +/- 3) years with unexplained syncope from Beijing, Hunan, Hubei and Shanghai and undergoing baseline head-up tilt tests (BHUTT) or head-up tilt tests potentiated with nitroglycerine (SNHUTT) under a quiet circumstance were selected as the syncope group. Ten healthy children (5 males, 5 females) aged 9-15 years with a mean age of (11.4 +/- 2.1) years, were recruited as the control group. SPSS 10.0 software was used for data analysis.

RESULTS

In 379 children with unexplained syncope, 67 (17.7%) were of postural orthostatic tachycardia syndrome (POTS), 157 (41.4%) of vasovagal syncope vasoinhibitory pattern, 14 (3.7%) of vasovagal syncope cardioinhibitory pattern, 47 (12.4%) of vasovagal syncope mixed pattern, 1 (0.3%) of orthostatic hypotension (OH) and 93 children (24.5%) of UPS. In syncope group and control group, the positive rate of BHUTT was 55.9% and 0 respectively and it was 75.5% and 20.0% respectively for SNHUTT. During BHUTT, the mean time of positive response occurrence was (16 +/- 12) minutes, and the posture when positive response appeared was at a tilt angle of 60 degrees. For SNHUTT, the mean time of positive response occurrence was (6 +/- 4) minutes and the posture was at a tilt angle of 60 degrees when potentiated with nitroglycerine.

CONCLUSION

HUTT is an objective diagnostic tool of UPS. With a high diagnostic positive rate, SNHUTT can improve the diagnostic positive rate of BHUTT. Meanwhile the time of positive response occurrence during SNHUTT is markedly shorter than BHUTT.

Authors+Show Affiliations

Chen L
Department of Pediatrics, Peking University First Hospital, Beijing 100034, China.
Wang C
No affiliation info available
Jin HF
No affiliation info available
Tian H
No affiliation info available
Wang L
No affiliation info available
Hu XF
No affiliation info available
Wang HW
No affiliation info available
Li WZ
No affiliation info available
Du ZD
No affiliation info available
Wang YL
No affiliation info available
Zhang QY
No affiliation info available
Du JB
No affiliation info available

MeSH

AdolescentChildChild, PreschoolFemaleHumansMaleSyncopeSyncope, VasovagalTilt-Table Test

Pub Type(s)

English Abstract
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

19950566

Citation

Chen, Li, et al. "[Diagnosis of Unexplained Syncope in Children: a Multi-center Study]." Zhonghua Yi Xue Za Zhi, vol. 89, no. 28, 2009, pp. 1947-50.
Chen L, Wang C, Jin HF, et al. [Diagnosis of unexplained syncope in children: a multi-center study]. Zhonghua Yi Xue Za Zhi. 2009;89(28):1947-50.
Chen, L., Wang, C., Jin, H. F., Tian, H., Wang, L., Hu, X. F., Wang, H. W., Li, W. Z., Du, Z. D., Wang, Y. L., Zhang, Q. Y., & Du, J. B. (2009). [Diagnosis of unexplained syncope in children: a multi-center study]. Zhonghua Yi Xue Za Zhi, 89(28), 1947-50.
Chen L, et al. [Diagnosis of Unexplained Syncope in Children: a Multi-center Study]. Zhonghua Yi Xue Za Zhi. 2009 Jul 28;89(28):1947-50. PubMed PMID: 19950566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Diagnosis of unexplained syncope in children: a multi-center study]. AU - Chen,Li, AU - Wang,Cheng, AU - Jin,Hong-Fang, AU - Tian,Hong, AU - Wang,Li, AU - Hu,Xiu-Fen, AU - Wang,Hong-Wei, AU - Li,Wan-Zhen, AU - Du,Zhong-Dong, AU - Wang,Yu-Li, AU - Zhang,Qing-You, AU - Du,Jun-Bao, PY - 2009/12/3/entrez PY - 2009/12/3/pubmed PY - 2010/3/10/medline SP - 1947 EP - 50 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 89 IS - 28 N2 - OBJECTIVE: To examine the diagnostic value of head-up tilt test in children with unexplained syncope (UPS). METHODS: A total of 379 children (171 males, 208 females) aged 3-18 years, mean age (12 +/- 3) years with unexplained syncope from Beijing, Hunan, Hubei and Shanghai and undergoing baseline head-up tilt tests (BHUTT) or head-up tilt tests potentiated with nitroglycerine (SNHUTT) under a quiet circumstance were selected as the syncope group. Ten healthy children (5 males, 5 females) aged 9-15 years with a mean age of (11.4 +/- 2.1) years, were recruited as the control group. SPSS 10.0 software was used for data analysis. RESULTS: In 379 children with unexplained syncope, 67 (17.7%) were of postural orthostatic tachycardia syndrome (POTS), 157 (41.4%) of vasovagal syncope vasoinhibitory pattern, 14 (3.7%) of vasovagal syncope cardioinhibitory pattern, 47 (12.4%) of vasovagal syncope mixed pattern, 1 (0.3%) of orthostatic hypotension (OH) and 93 children (24.5%) of UPS. In syncope group and control group, the positive rate of BHUTT was 55.9% and 0 respectively and it was 75.5% and 20.0% respectively for SNHUTT. During BHUTT, the mean time of positive response occurrence was (16 +/- 12) minutes, and the posture when positive response appeared was at a tilt angle of 60 degrees. For SNHUTT, the mean time of positive response occurrence was (6 +/- 4) minutes and the posture was at a tilt angle of 60 degrees when potentiated with nitroglycerine. CONCLUSION: HUTT is an objective diagnostic tool of UPS. With a high diagnostic positive rate, SNHUTT can improve the diagnostic positive rate of BHUTT. Meanwhile the time of positive response occurrence during SNHUTT is markedly shorter than BHUTT. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/19950566/[Diagnosis_of_unexplained_syncope_in_children:_a_multi_center_study]_ DB - PRIME DP - Unbound Medicine ER -