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Travel-related thromboembolism: mechanisms and avoidance.
Expert Rev Cardiovasc Ther. 2009 Dec; 7(12):1559-67.ER

Abstract

Evidence regarding the existence of travel-related venous thrombosis and pulmonary embolism is building. Research suggests that travel of all kinds increases the risk by two- to four-fold. Risks are not restricted to air travel alone. For travelers without any known risk factors, the risk of experiencing venous thromboembolism is likely to be very low. However, risks increase significantly in the presence of known risk factors, such as age over 60 years, thrombophilic disorders, varicose veins, history of thromboembolism, obesity, women taking oral contraceptives and travel duration over 12 h. A combination of one or more of these risk factors raises the probability of developing travel-related thromboembolism. Possible contributing factors, such as cramped sitting (with suppressed leg venous flow), moderate hypoxia, low humidity in the aircraft and dehydration, are discussed. Depending on the risk profile of individuals, the use of graduated compression stockings and/or pharmacological interventions (low-molecular-weight heparins are preferred) may be recommended.

Authors+Show Affiliations

Institute for Sports Medicine, Alpine Medicine & Health Tourism, TILAK Innsbruck and Private University for Health Sciences, Medical Informatics and Technology (UMIT), Eduard Wallnöfer-Zentrum 1, 6060 Hall, Austria. wolfgang.schobersberger@uki.atNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19954318

Citation

Schobersberger, Wolfgang, et al. "Travel-related Thromboembolism: Mechanisms and Avoidance." Expert Review of Cardiovascular Therapy, vol. 7, no. 12, 2009, pp. 1559-67.
Schobersberger W, Schobersberger B, Partsch H. Travel-related thromboembolism: mechanisms and avoidance. Expert Rev Cardiovasc Ther. 2009;7(12):1559-67.
Schobersberger, W., Schobersberger, B., & Partsch, H. (2009). Travel-related thromboembolism: mechanisms and avoidance. Expert Review of Cardiovascular Therapy, 7(12), 1559-67. https://doi.org/10.1586/erc.09.142
Schobersberger W, Schobersberger B, Partsch H. Travel-related Thromboembolism: Mechanisms and Avoidance. Expert Rev Cardiovasc Ther. 2009;7(12):1559-67. PubMed PMID: 19954318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Travel-related thromboembolism: mechanisms and avoidance. AU - Schobersberger,Wolfgang, AU - Schobersberger,Beatrix, AU - Partsch,Hugo, PY - 2009/12/4/entrez PY - 2009/12/4/pubmed PY - 2010/3/5/medline SP - 1559 EP - 67 JF - Expert review of cardiovascular therapy JO - Expert Rev Cardiovasc Ther VL - 7 IS - 12 N2 - Evidence regarding the existence of travel-related venous thrombosis and pulmonary embolism is building. Research suggests that travel of all kinds increases the risk by two- to four-fold. Risks are not restricted to air travel alone. For travelers without any known risk factors, the risk of experiencing venous thromboembolism is likely to be very low. However, risks increase significantly in the presence of known risk factors, such as age over 60 years, thrombophilic disorders, varicose veins, history of thromboembolism, obesity, women taking oral contraceptives and travel duration over 12 h. A combination of one or more of these risk factors raises the probability of developing travel-related thromboembolism. Possible contributing factors, such as cramped sitting (with suppressed leg venous flow), moderate hypoxia, low humidity in the aircraft and dehydration, are discussed. Depending on the risk profile of individuals, the use of graduated compression stockings and/or pharmacological interventions (low-molecular-weight heparins are preferred) may be recommended. SN - 1744-8344 UR - https://www.unboundmedicine.com/medline/citation/19954318/full_citation L2 - http://www.tandfonline.com/doi/full/10.1586/erc.09.142 DB - PRIME DP - Unbound Medicine ER -