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Fatty acids and immune function: relevance to inflammatory bowel diseases.
Int Rev Immunol. 2009; 28(6):506-34.IR

Abstract

Fatty acids may influence immune function through a variety of mechanisms; many of these are associated with changes in fatty acid composition of immune cell membranes. Eicosanoids produced from arachidonic acid have roles in inflammation and immunity. Increased membrane content of n-3 fatty acids results in a changed pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty acid composition of immune cells also affects T cell reactivity and antigen presentation. Little attention has been paid to the influence of fatty acids on the gut-associated lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation.

Authors+Show Affiliations

Institute of Human Nutrition, School of Medicine, University of Southampton, Southampton General Hospital, Southampton, United Kingdom. pcc@soton.ac.uk

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19954361

Citation

Calder, Philip C.. "Fatty Acids and Immune Function: Relevance to Inflammatory Bowel Diseases." International Reviews of Immunology, vol. 28, no. 6, 2009, pp. 506-34.
Calder PC. Fatty acids and immune function: relevance to inflammatory bowel diseases. Int Rev Immunol. 2009;28(6):506-34.
Calder, P. C. (2009). Fatty acids and immune function: relevance to inflammatory bowel diseases. International Reviews of Immunology, 28(6), 506-34. https://doi.org/10.3109/08830180903197480
Calder PC. Fatty Acids and Immune Function: Relevance to Inflammatory Bowel Diseases. Int Rev Immunol. 2009;28(6):506-34. PubMed PMID: 19954361.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatty acids and immune function: relevance to inflammatory bowel diseases. A1 - Calder,Philip C, PY - 2009/12/4/entrez PY - 2009/12/4/pubmed PY - 2010/3/6/medline SP - 506 EP - 34 JF - International reviews of immunology JO - Int. Rev. Immunol. VL - 28 IS - 6 N2 - Fatty acids may influence immune function through a variety of mechanisms; many of these are associated with changes in fatty acid composition of immune cell membranes. Eicosanoids produced from arachidonic acid have roles in inflammation and immunity. Increased membrane content of n-3 fatty acids results in a changed pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty acid composition of immune cells also affects T cell reactivity and antigen presentation. Little attention has been paid to the influence of fatty acids on the gut-associated lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation. SN - 1563-5244 UR - https://www.unboundmedicine.com/medline/citation/19954361/Fatty_acids_and_immune_function:_relevance_to_inflammatory_bowel_diseases_ L2 - http://www.tandfonline.com/doi/full/10.3109/08830180903197480 DB - PRIME DP - Unbound Medicine ER -