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Serum levels of Cu, Se, and Zn in adult rural/urban residents in Ghana: paradigm shift?
Biol Trace Elem Res. 2010 Nov; 137(2):139-49.BT

Abstract

Deficiencies in Cu, Se, and Zn impair one or more biochemical functions, and excess are associated with toxicity. Baseline studies on the Ghanaian population are scanty. The study was undertaken to determine whether significant rural/urban differences in the serum levels of Cu, Se, and Zn did exist. Forty males/60 females from rural and 50 males/50 females from urban Ghanaian communities were sampled. Serum Cu, Se, and Zn were determined using flame atomic absorption spectrometry. Cu level for rural and urban subjects was 997 +/- 333 and 979 +/- 290 microg/L, respectively (p = 0.68). However, Cu levels were significantly higher in the rural females (1,063 +/- 367 microg/L) than the rural males (898 +/- 249 microg/L; p = 0.0085). Se levels for rural/urban subjects were 97 +/- 36 and 87 +/- 31 microg/L, respectively (p = 0.03). Zn levels in the rural/urban subjects were 312 +/- 218 and 150 +/- 102 microg/L, respectively (p = 0.002). Additionally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than the urban females (166 +/- 103 microg/L; p = 0.0002). Finally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than males (172 +/- 116 microg/L; p = 0.0028). In conclusion, Cu, Se, and Zn were higher in the rural group compared to the urban group, and the generally low Zn levels were confirmed in another cohort follow-up study.

Authors+Show Affiliations

Chemical Pathology Unit, Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, University of Ghana, P.O. Box KB143, Accra, Ghana. gasare@chs.edu.ghNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19957050

Citation

Asare, George A., and Albert Nani. "Serum Levels of Cu, Se, and Zn in Adult Rural/urban Residents in Ghana: Paradigm Shift?" Biological Trace Element Research, vol. 137, no. 2, 2010, pp. 139-49.
Asare GA, Nani A. Serum levels of Cu, Se, and Zn in adult rural/urban residents in Ghana: paradigm shift? Biol Trace Elem Res. 2010;137(2):139-49.
Asare, G. A., & Nani, A. (2010). Serum levels of Cu, Se, and Zn in adult rural/urban residents in Ghana: paradigm shift? Biological Trace Element Research, 137(2), 139-49. https://doi.org/10.1007/s12011-009-8571-y
Asare GA, Nani A. Serum Levels of Cu, Se, and Zn in Adult Rural/urban Residents in Ghana: Paradigm Shift. Biol Trace Elem Res. 2010;137(2):139-49. PubMed PMID: 19957050.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum levels of Cu, Se, and Zn in adult rural/urban residents in Ghana: paradigm shift? AU - Asare,George A, AU - Nani,Albert, Y1 - 2009/12/03/ PY - 2009/09/24/received PY - 2009/11/10/accepted PY - 2009/12/4/entrez PY - 2009/12/4/pubmed PY - 2010/12/22/medline SP - 139 EP - 49 JF - Biological trace element research JO - Biol Trace Elem Res VL - 137 IS - 2 N2 - Deficiencies in Cu, Se, and Zn impair one or more biochemical functions, and excess are associated with toxicity. Baseline studies on the Ghanaian population are scanty. The study was undertaken to determine whether significant rural/urban differences in the serum levels of Cu, Se, and Zn did exist. Forty males/60 females from rural and 50 males/50 females from urban Ghanaian communities were sampled. Serum Cu, Se, and Zn were determined using flame atomic absorption spectrometry. Cu level for rural and urban subjects was 997 +/- 333 and 979 +/- 290 microg/L, respectively (p = 0.68). However, Cu levels were significantly higher in the rural females (1,063 +/- 367 microg/L) than the rural males (898 +/- 249 microg/L; p = 0.0085). Se levels for rural/urban subjects were 97 +/- 36 and 87 +/- 31 microg/L, respectively (p = 0.03). Zn levels in the rural/urban subjects were 312 +/- 218 and 150 +/- 102 microg/L, respectively (p = 0.002). Additionally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than the urban females (166 +/- 103 microg/L; p = 0.0002). Finally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than males (172 +/- 116 microg/L; p = 0.0028). In conclusion, Cu, Se, and Zn were higher in the rural group compared to the urban group, and the generally low Zn levels were confirmed in another cohort follow-up study. SN - 1559-0720 UR - https://www.unboundmedicine.com/medline/citation/19957050/Serum_levels_of_Cu_Se_and_Zn_in_adult_rural/urban_residents_in_Ghana:_paradigm_shift L2 - https://dx.doi.org/10.1007/s12011-009-8571-y DB - PRIME DP - Unbound Medicine ER -