Tags

Type your tag names separated by a space and hit enter

Peroxisomes are oxidative organelles.
Antioxid Redox Signal. 2010 Aug 15; 13(4):525-37.AR

Abstract

Peroxisomes are multifunctional organelles with an important role in the generation and decomposition of reactive oxygen species (ROS). In this review, the ROS-producing enzymes, as well as the antioxidative defense system in mammalian peroxisomes, are described. In addition, various conditions leading to disturbances in peroxisomal ROS metabolism, such as abnormal peroxisomal biogenesis, hypocatalasemia, and proliferation of peroxisomes are discussed. We also review the role of mammalian peroxisomes in some physiological and pathological processes involving ROS that lead to mitochondrial abnormalities, defects in cell proliferation, and alterations in the central nervous system, alcoholic cardiomyopathy, and aging. Antioxid.

Authors+Show Affiliations

Department of Biochemistry, University of Oulu, Oulu, Finland. vasily.antonenkov@oulu.fiNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19958170

Citation

Antonenkov, Vasily D., et al. "Peroxisomes Are Oxidative Organelles." Antioxidants & Redox Signaling, vol. 13, no. 4, 2010, pp. 525-37.
Antonenkov VD, Grunau S, Ohlmeier S, et al. Peroxisomes are oxidative organelles. Antioxid Redox Signal. 2010;13(4):525-37.
Antonenkov, V. D., Grunau, S., Ohlmeier, S., & Hiltunen, J. K. (2010). Peroxisomes are oxidative organelles. Antioxidants & Redox Signaling, 13(4), 525-37. https://doi.org/10.1089/ars.2009.2996
Antonenkov VD, et al. Peroxisomes Are Oxidative Organelles. Antioxid Redox Signal. 2010 Aug 15;13(4):525-37. PubMed PMID: 19958170.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Peroxisomes are oxidative organelles. AU - Antonenkov,Vasily D, AU - Grunau,Silke, AU - Ohlmeier,Steffen, AU - Hiltunen,J Kalervo, PY - 2009/12/5/entrez PY - 2009/12/5/pubmed PY - 2010/10/1/medline SP - 525 EP - 37 JF - Antioxidants & redox signaling JO - Antioxid Redox Signal VL - 13 IS - 4 N2 - Peroxisomes are multifunctional organelles with an important role in the generation and decomposition of reactive oxygen species (ROS). In this review, the ROS-producing enzymes, as well as the antioxidative defense system in mammalian peroxisomes, are described. In addition, various conditions leading to disturbances in peroxisomal ROS metabolism, such as abnormal peroxisomal biogenesis, hypocatalasemia, and proliferation of peroxisomes are discussed. We also review the role of mammalian peroxisomes in some physiological and pathological processes involving ROS that lead to mitochondrial abnormalities, defects in cell proliferation, and alterations in the central nervous system, alcoholic cardiomyopathy, and aging. Antioxid. SN - 1557-7716 UR - https://www.unboundmedicine.com/medline/citation/19958170/Peroxisomes_are_oxidative_organelles_ L2 - https://www.liebertpub.com/doi/10.1089/ars.2009.2996?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -