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Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry.
Am Heart J. 2009 Dec; 158(6):1038-45.AH

Abstract

BACKGROUND

Prior investigations to define ethnic-related differences in the risks, medical treatment, and outcomes of patients with peripheral arterial disease (PAD) have been limited.

METHODS

The impact of ethnicity on the risk factor profiles, use of evidence-based medical therapies, and 2-year cardiovascular outcomes were investigated in 2,168 individuals (blacks n = 237, Hispanics n = 115, whites n = 1,816) from the United States with PAD from the international Reduction of Atherothrombosis for Continued Health Registry.

RESULTS

Blacks and Hispanics were more likely to have diabetes mellitus and hypertension, whereas whites had a higher rate of diagnosed hypercholesterolemia. Control of blood pressure and cholesterol levels differed significantly in the groups at baseline: elevated blood pressure was present in 55% of blacks versus 48% of Hispanics versus 38% of whites (P < .01), whereas 41% of blacks versus 31% of Hispanics versus 25% of whites had elevated total cholesterol (P < .01). Aspirin use (62% of blacks vs 68% of Hispanics vs 72% of whites, P < .01) and statin use (72% of blacks vs 68% of Hispanics vs 77% of whites, P = .03) also varied significantly. In this context, rates by ethnicity for cardiovascular death, myocardial infarction, or stroke seemed to be no different at 2 years, at 8.8% for the total population: 11.6% for blacks, 8.5% for whites, and 5.0% for Hispanics (P = .32). Fewer blacks (0.6%) had undergone peripheral arterial bypass surgery compared with whites (3.4%) and Hispanics (5.2%) (P = .02).

CONCLUSIONS

Ethnic-related differences have been documented in the prevalence and treatment of several atherosclerotic risk factors known to be associated with PAD, including a variation in the use of surgical revascularization procedures.

Authors+Show Affiliations

Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19958873

Citation

Meadows, Telly A., et al. "Ethnic Differences in the Prevalence and Treatment of Cardiovascular Risk Factors in US Outpatients With Peripheral Arterial Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry." American Heart Journal, vol. 158, no. 6, 2009, pp. 1038-45.
Meadows TA, Bhatt DL, Hirsch AT, et al. Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. Am Heart J. 2009;158(6):1038-45.
Meadows, T. A., Bhatt, D. L., Hirsch, A. T., Creager, M. A., Califf, R. M., Ohman, E. M., Cannon, C. P., Eagle, K. A., Alberts, M. J., Goto, S., Smith, S. C., Wilson, P. W., Watson, K. E., & Steg, P. G. (2009). Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. American Heart Journal, 158(6), 1038-45. https://doi.org/10.1016/j.ahj.2009.09.014
Meadows TA, et al. Ethnic Differences in the Prevalence and Treatment of Cardiovascular Risk Factors in US Outpatients With Peripheral Arterial Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry. Am Heart J. 2009;158(6):1038-45. PubMed PMID: 19958873.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. AU - Meadows,Telly A, AU - Bhatt,Deepak L, AU - Hirsch,Alan T, AU - Creager,Mark A, AU - Califf,Robert M, AU - Ohman,E Magnus, AU - Cannon,Christopher P, AU - Eagle,Kim A, AU - Alberts,Mark J, AU - Goto,Shinya, AU - Smith,Sidney C,Jr AU - Wilson,Peter W F, AU - Watson,Karol E, AU - Steg,P Gabriel, AU - ,, PY - 2009/06/04/received PY - 2009/09/17/accepted PY - 2009/12/5/entrez PY - 2009/12/5/pubmed PY - 2010/1/7/medline SP - 1038 EP - 45 JF - American heart journal JO - Am. Heart J. VL - 158 IS - 6 N2 - BACKGROUND: Prior investigations to define ethnic-related differences in the risks, medical treatment, and outcomes of patients with peripheral arterial disease (PAD) have been limited. METHODS: The impact of ethnicity on the risk factor profiles, use of evidence-based medical therapies, and 2-year cardiovascular outcomes were investigated in 2,168 individuals (blacks n = 237, Hispanics n = 115, whites n = 1,816) from the United States with PAD from the international Reduction of Atherothrombosis for Continued Health Registry. RESULTS: Blacks and Hispanics were more likely to have diabetes mellitus and hypertension, whereas whites had a higher rate of diagnosed hypercholesterolemia. Control of blood pressure and cholesterol levels differed significantly in the groups at baseline: elevated blood pressure was present in 55% of blacks versus 48% of Hispanics versus 38% of whites (P < .01), whereas 41% of blacks versus 31% of Hispanics versus 25% of whites had elevated total cholesterol (P < .01). Aspirin use (62% of blacks vs 68% of Hispanics vs 72% of whites, P < .01) and statin use (72% of blacks vs 68% of Hispanics vs 77% of whites, P = .03) also varied significantly. In this context, rates by ethnicity for cardiovascular death, myocardial infarction, or stroke seemed to be no different at 2 years, at 8.8% for the total population: 11.6% for blacks, 8.5% for whites, and 5.0% for Hispanics (P = .32). Fewer blacks (0.6%) had undergone peripheral arterial bypass surgery compared with whites (3.4%) and Hispanics (5.2%) (P = .02). CONCLUSIONS: Ethnic-related differences have been documented in the prevalence and treatment of several atherosclerotic risk factors known to be associated with PAD, including a variation in the use of surgical revascularization procedures. SN - 1097-6744 UR - https://www.unboundmedicine.com/medline/citation/19958873/Ethnic_differences_in_the_prevalence_and_treatment_of_cardiovascular_risk_factors_in_US_outpatients_with_peripheral_arterial_disease:_insights_from_the_reduction_of_atherothrombosis_for_continued_health__REACH__registry_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-8703(09)00739-X DB - PRIME DP - Unbound Medicine ER -