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Catatonia and its treatment.
Schizophr Bull. 2010 Mar; 36(2):239-42.SB

Abstract

Psychiatric diagnoses are currently categorized on a syndromic basis. The syndrome of catatonia, however, remains in a diagnostic limbo, acknowledged predominantly as a subtype of schizophrenia. Yet, catatonia is present in about 10% of acutely ill psychiatry patients, only a minority of whom have schizophrenia. Among those with comorbid affective disorders, who comprise the largest subgroup of catatonic patients, the catatonic signs typically resolve dramatically and completely with benzodiazepine therapy. Those with schizophrenia respond less reliably, suggesting that the underlying processes causing the catatonia may be different in this group. The majority of patients with catatonia have concurrent psychosis. Failure to treat the catatonia before institution of antipsychotic medication may increase the risk of inducing neuroleptic malignant syndrome. At this point of time, the pathobiology of catatonia is unknown; the major reason for considering catatonia as a separate diagnostic entity would be to increase recognition of this eminently treatable neuropsychiatric syndrome.

Authors+Show Affiliations

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8P 3B6, Canada. Rosebush@HHSC.CANo affiliation info available

Pub Type(s)

Comment
Journal Article
Review

Language

eng

PubMed ID

19969591

Citation

Rosebush, Patricia I., and Michael F. Mazurek. "Catatonia and Its Treatment." Schizophrenia Bulletin, vol. 36, no. 2, 2010, pp. 239-42.
Rosebush PI, Mazurek MF. Catatonia and its treatment. Schizophr Bull. 2010;36(2):239-42.
Rosebush, P. I., & Mazurek, M. F. (2010). Catatonia and its treatment. Schizophrenia Bulletin, 36(2), 239-42. https://doi.org/10.1093/schbul/sbp141
Rosebush PI, Mazurek MF. Catatonia and Its Treatment. Schizophr Bull. 2010;36(2):239-42. PubMed PMID: 19969591.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Catatonia and its treatment. AU - Rosebush,Patricia I, AU - Mazurek,Michael F, Y1 - 2009/12/07/ PY - 2009/12/9/entrez PY - 2009/12/9/pubmed PY - 2010/6/3/medline SP - 239 EP - 42 JF - Schizophrenia bulletin JO - Schizophr Bull VL - 36 IS - 2 N2 - Psychiatric diagnoses are currently categorized on a syndromic basis. The syndrome of catatonia, however, remains in a diagnostic limbo, acknowledged predominantly as a subtype of schizophrenia. Yet, catatonia is present in about 10% of acutely ill psychiatry patients, only a minority of whom have schizophrenia. Among those with comorbid affective disorders, who comprise the largest subgroup of catatonic patients, the catatonic signs typically resolve dramatically and completely with benzodiazepine therapy. Those with schizophrenia respond less reliably, suggesting that the underlying processes causing the catatonia may be different in this group. The majority of patients with catatonia have concurrent psychosis. Failure to treat the catatonia before institution of antipsychotic medication may increase the risk of inducing neuroleptic malignant syndrome. At this point of time, the pathobiology of catatonia is unknown; the major reason for considering catatonia as a separate diagnostic entity would be to increase recognition of this eminently treatable neuropsychiatric syndrome. SN - 1745-1701 UR - https://www.unboundmedicine.com/medline/citation/19969591/Catatonia_and_its_treatment_ L2 - https://academic.oup.com/schizophreniabulletin/article-lookup/doi/10.1093/schbul/sbp141 DB - PRIME DP - Unbound Medicine ER -