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Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for african american adolescent females seeking sexual health services: a randomized controlled trial.
Arch Pediatr Adolesc Med. 2009 Dec; 163(12):1112-21.AP

Abstract

OBJECTIVES

To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators.

DESIGN

A randomized controlled trial of an HIV prevention program.

SETTING

Clinic-based sample in Atlanta, Georgia.

PARTICIPANTS

African American adolescent females (N = 715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computer-assisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure Incident chlamydial infections.

RESULTS

Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95% confidence interval [CI], 0.42 to 0.98; P = .04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95% CI, 0.08 to 0.83; P = .02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95% CI, 5.27 to 16.42; P < .001) and less frequent douching (mean difference, -0.76; 95% CI, -1.15 to -0.37; P = .001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95% CI, 1.09 to 1.80; P = .01) and condom use at last intercourse (RR, 1.30; 95% CI, 1.09 to 1.54; P = .005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors.

CONCLUSION

Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration clinicaltrials.gov Identifier: NCT00633906.

Authors+Show Affiliations

Department of Behavioral Sciences and Health Education, Rollins School of Public Health at Emory University, Atlanta, GA 30322, USA. rdiclem@emory.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19996048

Citation

DiClemente, Ralph J., et al. "Efficacy of Sexually Transmitted Disease/human Immunodeficiency Virus Sexual Risk-reduction Intervention for African American Adolescent Females Seeking Sexual Health Services: a Randomized Controlled Trial." Archives of Pediatrics & Adolescent Medicine, vol. 163, no. 12, 2009, pp. 1112-21.
DiClemente RJ, Wingood GM, Rose ES, et al. Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for african american adolescent females seeking sexual health services: a randomized controlled trial. Arch Pediatr Adolesc Med. 2009;163(12):1112-21.
DiClemente, R. J., Wingood, G. M., Rose, E. S., Sales, J. M., Lang, D. L., Caliendo, A. M., Hardin, J. W., & Crosby, R. A. (2009). Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for african american adolescent females seeking sexual health services: a randomized controlled trial. Archives of Pediatrics & Adolescent Medicine, 163(12), 1112-21. https://doi.org/10.1001/archpediatrics.2009.205
DiClemente RJ, et al. Efficacy of Sexually Transmitted Disease/human Immunodeficiency Virus Sexual Risk-reduction Intervention for African American Adolescent Females Seeking Sexual Health Services: a Randomized Controlled Trial. Arch Pediatr Adolesc Med. 2009;163(12):1112-21. PubMed PMID: 19996048.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for african american adolescent females seeking sexual health services: a randomized controlled trial. AU - DiClemente,Ralph J, AU - Wingood,Gina M, AU - Rose,Eve S, AU - Sales,Jessica M, AU - Lang,Delia L, AU - Caliendo,Angela M, AU - Hardin,James W, AU - Crosby,Richard A, PY - 2009/12/10/entrez PY - 2009/12/10/pubmed PY - 2010/1/27/medline SP - 1112 EP - 21 JF - Archives of pediatrics & adolescent medicine JO - Arch Pediatr Adolesc Med VL - 163 IS - 12 N2 - OBJECTIVES: To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators. DESIGN: A randomized controlled trial of an HIV prevention program. SETTING: Clinic-based sample in Atlanta, Georgia. PARTICIPANTS: African American adolescent females (N = 715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computer-assisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure Incident chlamydial infections. RESULTS: Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95% confidence interval [CI], 0.42 to 0.98; P = .04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95% CI, 0.08 to 0.83; P = .02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95% CI, 5.27 to 16.42; P < .001) and less frequent douching (mean difference, -0.76; 95% CI, -1.15 to -0.37; P = .001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95% CI, 1.09 to 1.80; P = .01) and condom use at last intercourse (RR, 1.30; 95% CI, 1.09 to 1.54; P = .005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors. CONCLUSION: Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration clinicaltrials.gov Identifier: NCT00633906. SN - 1538-3628 UR - https://www.unboundmedicine.com/medline/citation/19996048/Efficacy_of_sexually_transmitted_disease/human_immunodeficiency_virus_sexual_risk_reduction_intervention_for_african_american_adolescent_females_seeking_sexual_health_services:_a_randomized_controlled_trial_ L2 - https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/archpediatrics.2009.205 DB - PRIME DP - Unbound Medicine ER -