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Preoperative MUCP and VLPP did not predict long-term (4-year) outcome after transobturator mid-urethral sling.
Urol Int. 2009; 83(4):392-8.UI

Abstract

OBJECTIVE

Maximum urethral closure pressure (MUCP) and Valsalva leak point pressure (VLPP) have been considered objective parameters for studying the urethral integrity and predicting outcome after surgery for stress urinary incontinence (SUI). We test the hypothesis that preoperative MUCP and/or VLPP may predict long-term outcome after out-in transobturator tape (TOT) surgery for female SUI.

METHODS

65 patients affected by stress or mixed urinary incontinence were enrolled in a prospective observational descriptive study conducted from May 2002 to November 2005 at a single tertiary urban teaching university urogynecological department. Preoperative MUCP and VLPP, stratified as < or = or >40 cm H(2)O and < or = or >60 cm H(2)O, respectively, were separately or in combination correlated with primary (continence status: dry or wet) and secondary outcome variables (quality of life questionnaires) after surgery.

RESULTS

Out of 65 patients, 6 (9.2%) did not attend the follow-up. The median follow-up was 46 months (mean 52 +/- 18; range 36-82). The overall objective cure rates (dry) were 74.4% for patients with VLPP >60 cm H(2)O and 65% for VLPP < or =60 cm H(2)O (p < 0.654). The overall objective cure rates (dry) were 75% for patients with MUCP >40 cm H(2)O and 68.6% for MUCP < or =40 cm H(2)O (p < 0.808). The overall objective cure rates (dry) were 82.4% for patients with MUCP >40 cm H(2)O and VLPP >60 cm H(2)O and 69.2% for MUCP < or =40 cm H(2)O and VLPP < or =60 cm H(2)O (p < 0.956).

CONCLUSIONS

These data seem to cast doubts on the predictive value of MUCP and VLPP in patients who underwent TOT.

Authors+Show Affiliations

Section of Urology and Andrology, Department of Medical-Surgical Specialties and Public Health, University of Perugia, Perugia, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19996644

Citation

Costantini, Elisabetta, et al. "Preoperative MUCP and VLPP Did Not Predict Long-term (4-year) Outcome After Transobturator Mid-urethral Sling." Urologia Internationalis, vol. 83, no. 4, 2009, pp. 392-8.
Costantini E, Lazzeri M, Giannantoni A, et al. Preoperative MUCP and VLPP did not predict long-term (4-year) outcome after transobturator mid-urethral sling. Urol Int. 2009;83(4):392-8.
Costantini, E., Lazzeri, M., Giannantoni, A., Bini, V., del Zingaro, M., & Porena, M. (2009). Preoperative MUCP and VLPP did not predict long-term (4-year) outcome after transobturator mid-urethral sling. Urologia Internationalis, 83(4), 392-8. https://doi.org/10.1159/000251177
Costantini E, et al. Preoperative MUCP and VLPP Did Not Predict Long-term (4-year) Outcome After Transobturator Mid-urethral Sling. Urol Int. 2009;83(4):392-8. PubMed PMID: 19996644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preoperative MUCP and VLPP did not predict long-term (4-year) outcome after transobturator mid-urethral sling. AU - Costantini,Elisabetta, AU - Lazzeri,Massimo, AU - Giannantoni,Antonella, AU - Bini,Vittorio, AU - del Zingaro,Michele, AU - Porena,Massimo, Y1 - 2009/12/08/ PY - 2008/11/24/received PY - 2009/01/20/accepted PY - 2009/12/10/entrez PY - 2009/12/10/pubmed PY - 2010/5/21/medline SP - 392 EP - 8 JF - Urologia internationalis JO - Urol Int VL - 83 IS - 4 N2 - OBJECTIVE: Maximum urethral closure pressure (MUCP) and Valsalva leak point pressure (VLPP) have been considered objective parameters for studying the urethral integrity and predicting outcome after surgery for stress urinary incontinence (SUI). We test the hypothesis that preoperative MUCP and/or VLPP may predict long-term outcome after out-in transobturator tape (TOT) surgery for female SUI. METHODS: 65 patients affected by stress or mixed urinary incontinence were enrolled in a prospective observational descriptive study conducted from May 2002 to November 2005 at a single tertiary urban teaching university urogynecological department. Preoperative MUCP and VLPP, stratified as < or = or >40 cm H(2)O and < or = or >60 cm H(2)O, respectively, were separately or in combination correlated with primary (continence status: dry or wet) and secondary outcome variables (quality of life questionnaires) after surgery. RESULTS: Out of 65 patients, 6 (9.2%) did not attend the follow-up. The median follow-up was 46 months (mean 52 +/- 18; range 36-82). The overall objective cure rates (dry) were 74.4% for patients with VLPP >60 cm H(2)O and 65% for VLPP < or =60 cm H(2)O (p < 0.654). The overall objective cure rates (dry) were 75% for patients with MUCP >40 cm H(2)O and 68.6% for MUCP < or =40 cm H(2)O (p < 0.808). The overall objective cure rates (dry) were 82.4% for patients with MUCP >40 cm H(2)O and VLPP >60 cm H(2)O and 69.2% for MUCP < or =40 cm H(2)O and VLPP < or =60 cm H(2)O (p < 0.956). CONCLUSIONS: These data seem to cast doubts on the predictive value of MUCP and VLPP in patients who underwent TOT. SN - 1423-0399 UR - https://www.unboundmedicine.com/medline/citation/19996644/Preoperative_MUCP_and_VLPP_did_not_predict_long_term__4_year__outcome_after_transobturator_mid_urethral_sling_ L2 - https://www.karger.com?DOI=10.1159/000251177 DB - PRIME DP - Unbound Medicine ER -