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Diagnosis and management of acute gout.
Med Health R I 2009; 92(11):356-8MH

Abstract

A definitive diagnosis of acute gout is made by detection of monosodium urate crystals in the synovial fluid of an inflamed joint. However, when this is not feasible a clinical diagnosis can sometimes be made with reasonable accuracy. The mainstays of acute gout management are colchicine, NSAIDs, and systemic or intra-articular corticosteroids. NSAIDs are preferable to colchicine because of their more favorable side effect profile. Successful treatment occurs with the prompt initiation of high dose short half-life NSAIDS. Since many patients with gout have comorbidites that preclude the use of NSAIDS or colchicine, systemic corticosteroids are commonly used to treat acute gouty arthritis. Intra-articular injections are appropriate in the setting of mono- or oligoarticular involvement. Adequate duration of anti-inflammatory therapy and careful patient education are essential elements of successful therapy for acute gout. Evaluation and management of hyperuricemia should be undertaken when all symptoms of acute gout are resolved and the patient is stable on daily prophylaxis with NSAIDs or colchicine.

Authors+Show Affiliations

Conway N
Roger Williams Medical Center, USA.
Schwartz S
No affiliation info available

MeSH

Acute DiseaseAdrenal Cortex HormonesAdrenocorticotropic HormoneAnti-Inflammatory Agents, Non-SteroidalColchicineDiagnosis, DifferentialDrug Therapy, CombinationGoutGout SuppressantsHormonesHumansUricosuric Agents

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19999893

Citation

Conway, Nazli, and Stuart Schwartz. "Diagnosis and Management of Acute Gout." Medicine and Health, Rhode Island, vol. 92, no. 11, 2009, pp. 356-8.
Conway N, Schwartz S. Diagnosis and management of acute gout. Med Health R I. 2009;92(11):356-8.
Conway, N., & Schwartz, S. (2009). Diagnosis and management of acute gout. Medicine and Health, Rhode Island, 92(11), pp. 356-8.
Conway N, Schwartz S. Diagnosis and Management of Acute Gout. Med Health R I. 2009;92(11):356-8. PubMed PMID: 19999893.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and management of acute gout. AU - Conway,Nazli, AU - Schwartz,Stuart, PY - 2009/12/17/entrez PY - 2009/12/17/pubmed PY - 2010/1/22/medline SP - 356 EP - 8 JF - Medicine and health, Rhode Island JO - Med Health R I VL - 92 IS - 11 N2 - A definitive diagnosis of acute gout is made by detection of monosodium urate crystals in the synovial fluid of an inflamed joint. However, when this is not feasible a clinical diagnosis can sometimes be made with reasonable accuracy. The mainstays of acute gout management are colchicine, NSAIDs, and systemic or intra-articular corticosteroids. NSAIDs are preferable to colchicine because of their more favorable side effect profile. Successful treatment occurs with the prompt initiation of high dose short half-life NSAIDS. Since many patients with gout have comorbidites that preclude the use of NSAIDS or colchicine, systemic corticosteroids are commonly used to treat acute gouty arthritis. Intra-articular injections are appropriate in the setting of mono- or oligoarticular involvement. Adequate duration of anti-inflammatory therapy and careful patient education are essential elements of successful therapy for acute gout. Evaluation and management of hyperuricemia should be undertaken when all symptoms of acute gout are resolved and the patient is stable on daily prophylaxis with NSAIDs or colchicine. SN - 1086-5462 UR - https://www.unboundmedicine.com/medline/citation/19999893/Diagnosis_and_management_of_acute_gout_ L2 - https://medlineplus.gov/gout.html DB - PRIME DP - Unbound Medicine ER -