Tags

Type your tag names separated by a space and hit enter

The effects of smoking and smoking cessation on mortality from cardiovascular disease among Japanese: pooled analysis of three large-scale cohort studies in Japan.
Tob Control. 2010 Feb; 19(1):50-7.TC

Abstract

OBJECTIVES

To estimate the gender-specific risk of mortality from cardiovascular disease according to smoking status and time since smoking cessation among former smokers in Japan.

DESIGN

Prospective study.

SETTING

140,026 males and 156,810 females aged 40-79 years who participated in one of three cohort studies conducted in Japan between 1980 and 1990.

OUTCOME

The gender-specific hazard ratios (HRs) for cardiovascular disease mortality were calculated after adjustment for age and cohort.

RESULTS

The age-adjusted and cohort-adjusted HRs for current smokers compared with lifelong non-smokers were 1.51 (95% CI 1.38 to 1.64) for total cardiovascular diseases, 2.19 (95% CI 1.79 to 2.67) for coronary heart disease and 1.24 (95% CI 1.10 to 1.41) for total stroke in males, and were 1.85 (95% CI 1.65 to 2.06), 2.84 (95% CI 2.24 to 3.60) and 1.70 (95% CI 1.44 to 2.01), respectively, in females. The age-adjusted and cohort-adjusted HRs for former smokers compared with current smokers according to the time period since smoking cessation decreased by approximately 5 years after smoking cessation and reached the same level as lifelong non-smokers approximately 10 years after smoking cessation among both males and females.

CONCLUSIONS

The present study confirmed the association between smoking and mortality from cardiovascular disease in both males and females. Smoking cessation is a crucial preventive measure against death from cardiovascular disease.

Links

Publisher Full Text
Aggregator Full Text

Authors+Show Affiliations

Honjo K
Public Health, Department of Social and Environmental Health, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-9871, Japan.
Iso H
No affiliation info available
Tsugane S
No affiliation info available
Tamakoshi A
No affiliation info available
Satoh H
No affiliation info available
Tajima K
No affiliation info available
Suzuki T
No affiliation info available
Sobue T
No affiliation info available

MeSH

AdultAgedCardiovascular DiseasesCohort StudiesFemaleHumansJapanMaleMiddle AgedRisk FactorsSex FactorsSmokingSmoking CessationTime Factors

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20008160

Citation

Honjo, Kaori, et al. "The Effects of Smoking and Smoking Cessation On Mortality From Cardiovascular Disease Among Japanese: Pooled Analysis of Three Large-scale Cohort Studies in Japan." Tobacco Control, vol. 19, no. 1, 2010, pp. 50-7.
Honjo K, Iso H, Tsugane S, et al. The effects of smoking and smoking cessation on mortality from cardiovascular disease among Japanese: pooled analysis of three large-scale cohort studies in Japan. Tob Control. 2010;19(1):50-7.
Honjo, K., Iso, H., Tsugane, S., Tamakoshi, A., Satoh, H., Tajima, K., Suzuki, T., & Sobue, T. (2010). The effects of smoking and smoking cessation on mortality from cardiovascular disease among Japanese: pooled analysis of three large-scale cohort studies in Japan. Tobacco Control, 19(1), 50-7. https://doi.org/10.1136/tc.2009.029751
Honjo K, et al. The Effects of Smoking and Smoking Cessation On Mortality From Cardiovascular Disease Among Japanese: Pooled Analysis of Three Large-scale Cohort Studies in Japan. Tob Control. 2010;19(1):50-7. PubMed PMID: 20008160.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effects of smoking and smoking cessation on mortality from cardiovascular disease among Japanese: pooled analysis of three large-scale cohort studies in Japan. AU - Honjo,Kaori, AU - Iso,Hiroyasu, AU - Tsugane,Shoichiro, AU - Tamakoshi,Akiko, AU - Satoh,Hiroshi, AU - Tajima,Kazuo, AU - Suzuki,Takaichiro, AU - Sobue,Tomotaka, Y1 - 2009/12/11/ PY - 2009/12/17/entrez PY - 2009/12/17/pubmed PY - 2010/5/4/medline SP - 50 EP - 7 JF - Tobacco control JO - Tob Control VL - 19 IS - 1 N2 - OBJECTIVES: To estimate the gender-specific risk of mortality from cardiovascular disease according to smoking status and time since smoking cessation among former smokers in Japan. DESIGN: Prospective study. SETTING: 140,026 males and 156,810 females aged 40-79 years who participated in one of three cohort studies conducted in Japan between 1980 and 1990. OUTCOME: The gender-specific hazard ratios (HRs) for cardiovascular disease mortality were calculated after adjustment for age and cohort. RESULTS: The age-adjusted and cohort-adjusted HRs for current smokers compared with lifelong non-smokers were 1.51 (95% CI 1.38 to 1.64) for total cardiovascular diseases, 2.19 (95% CI 1.79 to 2.67) for coronary heart disease and 1.24 (95% CI 1.10 to 1.41) for total stroke in males, and were 1.85 (95% CI 1.65 to 2.06), 2.84 (95% CI 2.24 to 3.60) and 1.70 (95% CI 1.44 to 2.01), respectively, in females. The age-adjusted and cohort-adjusted HRs for former smokers compared with current smokers according to the time period since smoking cessation decreased by approximately 5 years after smoking cessation and reached the same level as lifelong non-smokers approximately 10 years after smoking cessation among both males and females. CONCLUSIONS: The present study confirmed the association between smoking and mortality from cardiovascular disease in both males and females. Smoking cessation is a crucial preventive measure against death from cardiovascular disease. SN - 1468-3318 UR - https://www.unboundmedicine.com/medline/citation/20008160/The_effects_of_smoking_and_smoking_cessation_on_mortality_from_cardiovascular_disease_among_Japanese:_pooled_analysis_of_three_large_scale_cohort_studies_in_Japan_ L2 - https://tobaccocontrol.bmj.com/lookup/pmidlookup?view=long&pmid=20008160 DB - PRIME DP - Unbound Medicine ER -