TY - JOUR T1 - Composition and biological activity of the essential oil from leaves of Plinia cerrocampanensis, a new source of alpha-bisabolol. AU - Vila,Roser, AU - Santana,Ana Isabel, AU - Pérez-Rosés,Renato, AU - Valderrama,Anayansi, AU - Castelli,M Victoria, AU - Mendonca,Sergio, AU - Zacchino,Susana, AU - Gupta,Mahabir P, AU - Cañigueral,Salvador, Y1 - 2009/12/16/ PY - 2009/07/28/received PY - 2009/10/28/revised PY - 2009/11/05/accepted PY - 2009/12/18/entrez PY - 2009/12/18/pubmed PY - 2010/4/24/medline SP - 2510 EP - 4 JF - Bioresource technology JO - Bioresour Technol VL - 101 IS - 7 N2 - The essential oil from fresh leaves of Plinia cerrocampanensis Barrie (Myrtaceae), obtained by hydrodistillation, was analysed by GC-FID and GC-MS. Forty components, representing more than 91% of the oil, were identified. Oxygenated sesquiterpenes represented the main fraction with alpha-bisabolol (42.8%) as the major constituent, making this plant a new and good source of this substance. Biological activity of the essential oil was evaluated against several bacterial and fungal strains as well as larvae from Aedes aegypti. The highest activity was found against Staphylococcus aureus, Pseudomonas aeruginosa, Microsporum gypseum, Trichophyton mentagrophytes and Trichophyton rubrum with MIC values from 32 to 125 microg/ml. The essential oil also showed potent inhibitory and bactericidal activities against three H. pylori strains, with MIC and MBC values of 62.5 microg/ml, and caused 100% mortality of A. aegypti larvae at a concentration of 500 microg/ml. SN - 1873-2976 UR - https://www.unboundmedicine.com/medline/citation/20015638/Composition_and_biological_activity_of_the_essential_oil_from_leaves_of_Plinia_cerrocampanensis_a_new_source_of_alpha_bisabolol_ DB - PRIME DP - Unbound Medicine ER -