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Coeliac disease and reproductive disorders.
Scand J Gastroenterol 2010; 45(4):395-402SJ

Abstract

Reproductive problems, such as delayed menarche, amenorrhea, early menopause, infertility, impotence, hypogonadism, recurrent abortions, and low-birth-weight or preterm deliveries, are now known to be among the atypical symptoms of coeliac disease (CD). The pathogenesis of reproductive disorders in CD is unclear, but some hypotheses have been suggested, including autoimmunity and macro- and/or micronutrient deficiency. Recent investigations which have focused on tissue transglutaminase are promising with respect to the clarification of the mechanism of infertility and poor pregnancy outcomes in CD. In this review, the effects of CD on male and female reproductive disorders and pregnancy outcomes are discussed and the need for CD screening in the case of reproductive problems is emphasized.

Authors+Show Affiliations

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Faculty of Medicine, Inönü University, Malatya, Turkey.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20017709

Citation

Ozgör, Bilge, and Mukadder Ayşe Selimoğlu. "Coeliac Disease and Reproductive Disorders." Scandinavian Journal of Gastroenterology, vol. 45, no. 4, 2010, pp. 395-402.
Ozgör B, Selimoğlu MA. Coeliac disease and reproductive disorders. Scand J Gastroenterol. 2010;45(4):395-402.
Ozgör, B., & Selimoğlu, M. A. (2010). Coeliac disease and reproductive disorders. Scandinavian Journal of Gastroenterology, 45(4), pp. 395-402. doi:10.3109/00365520903508902.
Ozgör B, Selimoğlu MA. Coeliac Disease and Reproductive Disorders. Scand J Gastroenterol. 2010;45(4):395-402. PubMed PMID: 20017709.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coeliac disease and reproductive disorders. AU - Ozgör,Bilge, AU - Selimoğlu,Mukadder Ayşe, PY - 2009/12/19/entrez PY - 2009/12/19/pubmed PY - 2010/7/16/medline SP - 395 EP - 402 JF - Scandinavian journal of gastroenterology JO - Scand. J. Gastroenterol. VL - 45 IS - 4 N2 - Reproductive problems, such as delayed menarche, amenorrhea, early menopause, infertility, impotence, hypogonadism, recurrent abortions, and low-birth-weight or preterm deliveries, are now known to be among the atypical symptoms of coeliac disease (CD). The pathogenesis of reproductive disorders in CD is unclear, but some hypotheses have been suggested, including autoimmunity and macro- and/or micronutrient deficiency. Recent investigations which have focused on tissue transglutaminase are promising with respect to the clarification of the mechanism of infertility and poor pregnancy outcomes in CD. In this review, the effects of CD on male and female reproductive disorders and pregnancy outcomes are discussed and the need for CD screening in the case of reproductive problems is emphasized. SN - 1502-7708 UR - https://www.unboundmedicine.com/medline/citation/20017709/Coeliac_disease_and_reproductive_disorders_ L2 - http://www.tandfonline.com/doi/full/10.3109/00365520903508902 DB - PRIME DP - Unbound Medicine ER -