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Serologic response to rabies pre-exposure vaccination in persons with potential occupational exposure in Singapore.
Int J Infect Dis. 2010 Jun; 14(6):e511-3.IJ

Abstract

Sixty-six animal workers received primary rabies vaccination with purified Vero cell vaccine (PVRV, Verorab). One year later, 26 (39%) demonstrated antibody titers below the recommended minimum of 0.5 IU/ml, and required a booster. All 15 of a separate group reporting primary vaccination with at least one booster had titers above 0.5 IU/ml 1 year later, demonstrating long-term boostable immunity. Rabies antibody titers should be checked 1 year after primary rabies vaccination in persons at high risk of frequent rabies exposure. If access to serological surveillance is unavailable, such high-risk individuals should receive booster vaccination.

Authors+Show Affiliations

Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433 Singapore. pllim@post.harvard.eduNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20018545

Citation

Lim, Poh Lian, and Timothy M S. Barkham. "Serologic Response to Rabies Pre-exposure Vaccination in Persons With Potential Occupational Exposure in Singapore." International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, vol. 14, no. 6, 2010, pp. e511-3.
Lim PL, Barkham TM. Serologic response to rabies pre-exposure vaccination in persons with potential occupational exposure in Singapore. Int J Infect Dis. 2010;14(6):e511-3.
Lim, P. L., & Barkham, T. M. (2010). Serologic response to rabies pre-exposure vaccination in persons with potential occupational exposure in Singapore. International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 14(6), e511-3. https://doi.org/10.1016/j.ijid.2009.08.008
Lim PL, Barkham TM. Serologic Response to Rabies Pre-exposure Vaccination in Persons With Potential Occupational Exposure in Singapore. Int J Infect Dis. 2010;14(6):e511-3. PubMed PMID: 20018545.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serologic response to rabies pre-exposure vaccination in persons with potential occupational exposure in Singapore. AU - Lim,Poh Lian, AU - Barkham,Timothy M S, Y1 - 2009/12/16/ PY - 2009/06/24/received PY - 2009/08/11/revised PY - 2009/08/11/accepted PY - 2009/12/19/entrez PY - 2009/12/19/pubmed PY - 2010/9/10/medline SP - e511 EP - 3 JF - International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases JO - Int J Infect Dis VL - 14 IS - 6 N2 - Sixty-six animal workers received primary rabies vaccination with purified Vero cell vaccine (PVRV, Verorab). One year later, 26 (39%) demonstrated antibody titers below the recommended minimum of 0.5 IU/ml, and required a booster. All 15 of a separate group reporting primary vaccination with at least one booster had titers above 0.5 IU/ml 1 year later, demonstrating long-term boostable immunity. Rabies antibody titers should be checked 1 year after primary rabies vaccination in persons at high risk of frequent rabies exposure. If access to serological surveillance is unavailable, such high-risk individuals should receive booster vaccination. SN - 1878-3511 UR - https://www.unboundmedicine.com/medline/citation/20018545/Serologic_response_to_rabies_pre_exposure_vaccination_in_persons_with_potential_occupational_exposure_in_Singapore_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(09)00342-7 DB - PRIME DP - Unbound Medicine ER -