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Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature.

Abstract

Age, obesity and family history of diabetes are well known risk factors for gestational diabetes mellitus. Others are more controversial. The objective of this review is to find evidence in the literature that justifies the inclusion of these other conditions among risk factors. The MEDLINE, Cochrane, LILACS and Pan American Health Organization databases were searched, covering articles dating from between 1992 and 2006. Keywords were used in combination (AND) with gestational diabetes mellitus separately and with each one of the risk factors studied. The methodological quality of the studies included was assessed, resulting in the selection of 41 papers. Most studies investigating maternal history of low birth weight, low stature, and low level of physical activity have found positive associations with gestational diabetes mellitus. Low socioeconomic levels, smoking during pregnancy, high parity, belonging to minority groups, and excessive weight gain during pregnancy presented conflicting results. Publication bias cannot be ruled out. Standardization of techniques, cutoff points for screening and diagnosis, as well as studies involving larger sample sizes would allow future meta-analyses.

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  • Authors+Show Affiliations

    ,

    Universidade Federal de Pelotas, Pelotas, Brasil. malicedode@terra.com.br

    Source

    Cadernos de saude publica 25 Suppl 3: 2009 pg S341-59

    MeSH

    Birth Weight
    Body Height
    Diabetes, Gestational
    Exercise
    Female
    Gestational Age
    Humans
    Parity
    Pregnancy
    Risk Factors
    Smoking
    Socioeconomic Factors

    Pub Type(s)

    Journal Article
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    20027384

    Citation

    Dode, Maria Alice Souza de Oliveira, and Iná S. dos Santos. "Non Classical Risk Factors for Gestational Diabetes Mellitus: a Systematic Review of the Literature." Cadernos De Saude Publica, vol. 25 Suppl 3, 2009, pp. S341-59.
    Dode MA, dos Santos IS. Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature. Cad Saude Publica. 2009;25 Suppl 3:S341-59.
    Dode, M. A., & dos Santos, I. S. (2009). Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature. Cadernos De Saude Publica, 25 Suppl 3, pp. S341-59.
    Dode MA, dos Santos IS. Non Classical Risk Factors for Gestational Diabetes Mellitus: a Systematic Review of the Literature. Cad Saude Publica. 2009;25 Suppl 3:S341-59. PubMed PMID: 20027384.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature. AU - Dode,Maria Alice Souza de Oliveira, AU - dos Santos,Iná S, PY - 2009/04/28/received PY - 2009/08/19/accepted PY - 2009/12/23/entrez PY - 2010/1/21/pubmed PY - 2010/12/14/medline SP - S341 EP - 59 JF - Cadernos de saude publica JO - Cad Saude Publica VL - 25 Suppl 3 N2 - Age, obesity and family history of diabetes are well known risk factors for gestational diabetes mellitus. Others are more controversial. The objective of this review is to find evidence in the literature that justifies the inclusion of these other conditions among risk factors. The MEDLINE, Cochrane, LILACS and Pan American Health Organization databases were searched, covering articles dating from between 1992 and 2006. Keywords were used in combination (AND) with gestational diabetes mellitus separately and with each one of the risk factors studied. The methodological quality of the studies included was assessed, resulting in the selection of 41 papers. Most studies investigating maternal history of low birth weight, low stature, and low level of physical activity have found positive associations with gestational diabetes mellitus. Low socioeconomic levels, smoking during pregnancy, high parity, belonging to minority groups, and excessive weight gain during pregnancy presented conflicting results. Publication bias cannot be ruled out. Standardization of techniques, cutoff points for screening and diagnosis, as well as studies involving larger sample sizes would allow future meta-analyses. SN - 1678-4464 UR - https://www.unboundmedicine.com/medline/citation/20027384/full_citation L2 - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2009001500002&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -