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Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process.
J Org Chem. 2010 Feb 05; 75(3):582-8.JO

Abstract

General and efficient methods for the construction of five-membered aromatic and nonaromatic heterocycles by palladium-catalyzed coupling/cycloisomerization of 1,6-enynes and aryl halides have been developed. Results indicate that substituents at the terminus of the alkynes have a significant effect on the selective formation of the products.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Meng TJ
Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, Institute of Organic Chemistry, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China.
Hu Y
No affiliation info available
Wang S
No affiliation info available

MeSH

AlkynesCatalysisCyclizationHeterocyclic CompoundsMolecular StructurePalladiumStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20030303

Citation

Meng, Tuan-Jie, et al. "Efficient Construction of Five-membered Aromatic and Nonaromatic Heterocycles From 1,6-enynes By a Palladium-catalyzed Domino Coupling/cycloisomerization Process." The Journal of Organic Chemistry, vol. 75, no. 3, 2010, pp. 582-8.
Meng TJ, Hu Y, Wang S. Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process. J Org Chem. 2010;75(3):582-8.
Meng, T. J., Hu, Y., & Wang, S. (2010). Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process. The Journal of Organic Chemistry, 75(3), 582-8. https://doi.org/10.1021/jo9020776
Meng TJ, Hu Y, Wang S. Efficient Construction of Five-membered Aromatic and Nonaromatic Heterocycles From 1,6-enynes By a Palladium-catalyzed Domino Coupling/cycloisomerization Process. J Org Chem. 2010 Feb 5;75(3):582-8. PubMed PMID: 20030303.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process. AU - Meng,Tuan-Jie, AU - Hu,Yimin, AU - Wang,Shaowu, PY - 2009/12/25/entrez PY - 2009/12/25/pubmed PY - 2010/4/7/medline SP - 582 EP - 8 JF - The Journal of organic chemistry JO - J Org Chem VL - 75 IS - 3 N2 - General and efficient methods for the construction of five-membered aromatic and nonaromatic heterocycles by palladium-catalyzed coupling/cycloisomerization of 1,6-enynes and aryl halides have been developed. Results indicate that substituents at the terminus of the alkynes have a significant effect on the selective formation of the products. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/20030303/Efficient_construction_of_five_membered_aromatic_and_nonaromatic_heterocycles_from_16_enynes_by_a_palladium_catalyzed_domino_coupling/cycloisomerization_process_ L2 - https://doi.org/10.1021/jo9020776 DB - PRIME DP - Unbound Medicine ER -