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Antioxidant activities and xanthine oxidase inhibitory effects of phenolic phytochemicals from Acacia confusa twigs and branches.
J Agric Food Chem. 2010 Feb 10; 58(3):1578-83.JA

Abstract

This study investigates bioactivities and active phytochemicals of the extracts of twigs and branches from the indigenous Taiwanese tree Acacia confusa Merr. The bioassay-guided fractionation yielded 8 potent antioxidative phytochemicals. Catechins are the major components in the extract of 5 cm branch bark, including catechin, catechin-3-O-rhamnopyranoside, epi-catechin, and quercetin-3-O-rhamnopyranoside, while flavonol glycosides are the major components in twig extract, namely, myricetin-3-O-glucopyranoside, myricetin-3-O-rhamnopyranoside, quercetin-3-O-rhamnopyranoside, myricetin-3-O-(2''-O-galloyl)-alpha-rhamnopyranoside, and luteolin. Of the test compounds, myricetin-3-O-(2''-O-galloyl)-alpha-rhamnopyranoside exhibited the highest antioxidant activity against DPPH radicals, showing a 2.8-fold lower IC(50) value of 5.3 microM related to that of quercetin. On the other hand, catechins apparently had no XOD inhibitory effect apart from their good antioxidant activities, while luteolin exhibited excellent activity against XOD with an IC(50) value of 11.6 microM. These results may provide useful information for future studies on the applications of A. confusa to be used as a source for natural health products.

Authors+Show Affiliations

School of Forestry and Resource Conservation, National Taiwan University, Taipei 106, Taiwan.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20030403

Citation

Hsieh, Ching-Yu, and Shang-Tzen Chang. "Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Phenolic Phytochemicals From Acacia Confusa Twigs and Branches." Journal of Agricultural and Food Chemistry, vol. 58, no. 3, 2010, pp. 1578-83.
Hsieh CY, Chang ST. Antioxidant activities and xanthine oxidase inhibitory effects of phenolic phytochemicals from Acacia confusa twigs and branches. J Agric Food Chem. 2010;58(3):1578-83.
Hsieh, C. Y., & Chang, S. T. (2010). Antioxidant activities and xanthine oxidase inhibitory effects of phenolic phytochemicals from Acacia confusa twigs and branches. Journal of Agricultural and Food Chemistry, 58(3), 1578-83. https://doi.org/10.1021/jf903569k
Hsieh CY, Chang ST. Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Phenolic Phytochemicals From Acacia Confusa Twigs and Branches. J Agric Food Chem. 2010 Feb 10;58(3):1578-83. PubMed PMID: 20030403.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activities and xanthine oxidase inhibitory effects of phenolic phytochemicals from Acacia confusa twigs and branches. AU - Hsieh,Ching-Yu, AU - Chang,Shang-Tzen, PY - 2009/12/25/entrez PY - 2009/12/25/pubmed PY - 2010/4/20/medline SP - 1578 EP - 83 JF - Journal of agricultural and food chemistry JO - J. Agric. Food Chem. VL - 58 IS - 3 N2 - This study investigates bioactivities and active phytochemicals of the extracts of twigs and branches from the indigenous Taiwanese tree Acacia confusa Merr. The bioassay-guided fractionation yielded 8 potent antioxidative phytochemicals. Catechins are the major components in the extract of 5 cm branch bark, including catechin, catechin-3-O-rhamnopyranoside, epi-catechin, and quercetin-3-O-rhamnopyranoside, while flavonol glycosides are the major components in twig extract, namely, myricetin-3-O-glucopyranoside, myricetin-3-O-rhamnopyranoside, quercetin-3-O-rhamnopyranoside, myricetin-3-O-(2''-O-galloyl)-alpha-rhamnopyranoside, and luteolin. Of the test compounds, myricetin-3-O-(2''-O-galloyl)-alpha-rhamnopyranoside exhibited the highest antioxidant activity against DPPH radicals, showing a 2.8-fold lower IC(50) value of 5.3 microM related to that of quercetin. On the other hand, catechins apparently had no XOD inhibitory effect apart from their good antioxidant activities, while luteolin exhibited excellent activity against XOD with an IC(50) value of 11.6 microM. These results may provide useful information for future studies on the applications of A. confusa to be used as a source for natural health products. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/20030403/Antioxidant_activities_and_xanthine_oxidase_inhibitory_effects_of_phenolic_phytochemicals_from_Acacia_confusa_twigs_and_branches_ L2 - https://dx.doi.org/10.1021/jf903569k DB - PRIME DP - Unbound Medicine ER -