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The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction.
Behav Brain Res. 2010 Apr 02; 208(2):646-9.BB

Abstract

Recent findings show that the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction is both context and stimulus specific. In this study we examined whether this switch was temporally specific as well. Re-extinction was found to be NMDAr-independent when it occurred 2 days after initial extinction but NMDAr-dependent when it occurred 21 days following initial extinction, thereby illustrating the importance of time as a type of context that modulates the mechanisms involved in extinction.

Authors+Show Affiliations

School of Psychology, University of New South Wales, Sydney, NSW, Australia. jlangton@psy.unsw.edu.auNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20035796

Citation

Langton, Julia M., and Rick Richardson. "The Temporal Specificity of the Switch From NMDAr-dependent Extinction to NMDAr-independent Re-extinction." Behavioural Brain Research, vol. 208, no. 2, 2010, pp. 646-9.
Langton JM, Richardson R. The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction. Behav Brain Res. 2010;208(2):646-9.
Langton, J. M., & Richardson, R. (2010). The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction. Behavioural Brain Research, 208(2), 646-9. https://doi.org/10.1016/j.bbr.2009.12.018
Langton JM, Richardson R. The Temporal Specificity of the Switch From NMDAr-dependent Extinction to NMDAr-independent Re-extinction. Behav Brain Res. 2010 Apr 2;208(2):646-9. PubMed PMID: 20035796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction. AU - Langton,Julia M, AU - Richardson,Rick, Y1 - 2009/12/24/ PY - 2009/10/13/received PY - 2009/12/14/revised PY - 2009/12/16/accepted PY - 2009/12/29/entrez PY - 2009/12/29/pubmed PY - 2010/5/26/medline SP - 646 EP - 9 JF - Behavioural brain research JO - Behav Brain Res VL - 208 IS - 2 N2 - Recent findings show that the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction is both context and stimulus specific. In this study we examined whether this switch was temporally specific as well. Re-extinction was found to be NMDAr-independent when it occurred 2 days after initial extinction but NMDAr-dependent when it occurred 21 days following initial extinction, thereby illustrating the importance of time as a type of context that modulates the mechanisms involved in extinction. SN - 1872-7549 UR - https://www.unboundmedicine.com/medline/citation/20035796/The_temporal_specificity_of_the_switch_from_NMDAr_dependent_extinction_to_NMDAr_independent_re_extinction_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0166-4328(09)00744-X DB - PRIME DP - Unbound Medicine ER -