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Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline.
Eur J Med Chem. 2010 Mar; 45(3):1128-32.EJ

Abstract

A series of new alpha-hydroxyphosphonate and alpha-acetoxyphosphonate derivatives have been synthesized for the first time of tetrazolo [1, 5-a] quinoline derivatives. Elemental analysis, IR, (1)H NMR, (13)C NMR and mass spectral data elucidated the structures of the all newly synthesized compounds. In vitro antimicrobial activities of the synthesized compounds were investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli and fungi Candida albicans and Aspergillus niger. Some of the tested compounds showed significant antimicrobial activity.

Authors+Show Affiliations

Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, Maharashtra, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20036039

Citation

Kategaonkar, Amol H., et al. "Synthesis, in Vitro Antibacterial and Antifungal Evaluations of New Alpha-hydroxyphosphonate and New Alpha-acetoxyphosphonate Derivatives of Tetrazolo [1, 5-a] Quinoline." European Journal of Medicinal Chemistry, vol. 45, no. 3, 2010, pp. 1128-32.
Kategaonkar AH, Pokalwar RU, Sonar SS, et al. Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. Eur J Med Chem. 2010;45(3):1128-32.
Kategaonkar, A. H., Pokalwar, R. U., Sonar, S. S., Gawali, V. U., Shingate, B. B., & Shingare, M. S. (2010). Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. European Journal of Medicinal Chemistry, 45(3), 1128-32. https://doi.org/10.1016/j.ejmech.2009.12.013
Kategaonkar AH, et al. Synthesis, in Vitro Antibacterial and Antifungal Evaluations of New Alpha-hydroxyphosphonate and New Alpha-acetoxyphosphonate Derivatives of Tetrazolo [1, 5-a] Quinoline. Eur J Med Chem. 2010;45(3):1128-32. PubMed PMID: 20036039.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. AU - Kategaonkar,Amol H, AU - Pokalwar,Rajkumar U, AU - Sonar,Swapnil S, AU - Gawali,Vaibhav U, AU - Shingate,Bapurao B, AU - Shingare,Murlidhar S, Y1 - 2009/12/24/ PY - 2009/07/27/received PY - 2009/11/23/revised PY - 2009/12/04/accepted PY - 2009/12/29/entrez PY - 2009/12/29/pubmed PY - 2010/7/23/medline SP - 1128 EP - 32 JF - European journal of medicinal chemistry JO - Eur J Med Chem VL - 45 IS - 3 N2 - A series of new alpha-hydroxyphosphonate and alpha-acetoxyphosphonate derivatives have been synthesized for the first time of tetrazolo [1, 5-a] quinoline derivatives. Elemental analysis, IR, (1)H NMR, (13)C NMR and mass spectral data elucidated the structures of the all newly synthesized compounds. In vitro antimicrobial activities of the synthesized compounds were investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli and fungi Candida albicans and Aspergillus niger. Some of the tested compounds showed significant antimicrobial activity. SN - 1768-3254 UR - https://www.unboundmedicine.com/medline/citation/20036039/Synthesis_in_vitro_antibacterial_and_antifungal_evaluations_of_new_alpha_hydroxyphosphonate_and_new_alpha_acetoxyphosphonate_derivatives_of_tetrazolo_[1_5_a]_quinoline_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0223-5234(09)00639-4 DB - PRIME DP - Unbound Medicine ER -