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Recent approaches for enhancing sensitivity in enantioseparations by CE.
Electrophoresis. 2010 Jan; 31(1):28-43.E

Abstract

This article reviews the latest methodological and instrumental improvements for enhancing sensitivity in chiral analysis by CE. The review covers literature from March 2007 until May 2009, that is, the works published after the appearance of the latest review article on the same topic by Sánchez-Hernández et al. [Electrophoresis 2008, 29, 237-251]. Off-line and on-line sample treatment techniques, on-line sample preconcentration strategies based on electrophoretic and chromatographic principles, and alternative detection systems to the widely employed UV/Vis detection in CE are the most relevant approaches discussed for improving sensitivity. Microchip technologies are also included since they can open up great possibilities to achieve sensitive and fast enantiomeric separations.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Sánchez-Hernández L
Departamento de Química Analítica, Universidad de Alcalá, Madrid, Spain.
García-Ruiz C
No affiliation info available
Luisa Marina M
No affiliation info available
Luis Crego A
No affiliation info available

MeSH

Chemical FractionationElectrophoresis, CapillaryPharmaceutical PreparationsProteinsSensitivity and SpecificityStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

20039292

Citation

Sánchez-Hernández, Laura, et al. "Recent Approaches for Enhancing Sensitivity in Enantioseparations By CE." Electrophoresis, vol. 31, no. 1, 2010, pp. 28-43.
Sánchez-Hernández L, García-Ruiz C, Luisa Marina M, et al. Recent approaches for enhancing sensitivity in enantioseparations by CE. Electrophoresis. 2010;31(1):28-43.
Sánchez-Hernández, L., García-Ruiz, C., Luisa Marina, M., & Luis Crego, A. (2010). Recent approaches for enhancing sensitivity in enantioseparations by CE. Electrophoresis, 31(1), 28-43. https://doi.org/10.1002/elps.200900429
Sánchez-Hernández L, et al. Recent Approaches for Enhancing Sensitivity in Enantioseparations By CE. Electrophoresis. 2010;31(1):28-43. PubMed PMID: 20039292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent approaches for enhancing sensitivity in enantioseparations by CE. AU - Sánchez-Hernández,Laura, AU - García-Ruiz,Carmen, AU - Luisa Marina,María, AU - Luis Crego,Antonio, PY - 2009/12/30/entrez PY - 2009/12/30/pubmed PY - 2010/3/5/medline SP - 28 EP - 43 JF - Electrophoresis JO - Electrophoresis VL - 31 IS - 1 N2 - This article reviews the latest methodological and instrumental improvements for enhancing sensitivity in chiral analysis by CE. The review covers literature from March 2007 until May 2009, that is, the works published after the appearance of the latest review article on the same topic by Sánchez-Hernández et al. [Electrophoresis 2008, 29, 237-251]. Off-line and on-line sample treatment techniques, on-line sample preconcentration strategies based on electrophoretic and chromatographic principles, and alternative detection systems to the widely employed UV/Vis detection in CE are the most relevant approaches discussed for improving sensitivity. Microchip technologies are also included since they can open up great possibilities to achieve sensitive and fast enantiomeric separations. SN - 1522-2683 UR - https://www.unboundmedicine.com/medline/citation/20039292/Recent_approaches_for_enhancing_sensitivity_in_enantioseparations_by_CE_ L2 - https://doi.org/10.1002/elps.200900429 DB - PRIME DP - Unbound Medicine ER -