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Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes.
J Am Chem Soc. 2010 Jan 27; 132(3):916-7.JA

Abstract

An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven-membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Han J
Department of Chemistry, University of Louisville, Louisville, Kentucky 40292, USA.
Xu B
No affiliation info available
Hammond GB
No affiliation info available

MeSH

AlkynesCatalysisCopperCyclizationHeterocyclic CompoundsMolecular StructureOrganometallic Compounds

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20041710

Citation

Han, Junbin, et al. "Highly Efficient Cu(I)-catalyzed Synthesis of N-heterocycles Through a Cyclization-triggered Addition of Alkynes." Journal of the American Chemical Society, vol. 132, no. 3, 2010, pp. 916-7.
Han J, Xu B, Hammond GB. Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes. J Am Chem Soc. 2010;132(3):916-7.
Han, J., Xu, B., & Hammond, G. B. (2010). Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes. Journal of the American Chemical Society, 132(3), 916-7. https://doi.org/10.1021/ja908883n
Han J, Xu B, Hammond GB. Highly Efficient Cu(I)-catalyzed Synthesis of N-heterocycles Through a Cyclization-triggered Addition of Alkynes. J Am Chem Soc. 2010 Jan 27;132(3):916-7. PubMed PMID: 20041710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes. AU - Han,Junbin, AU - Xu,Bo, AU - Hammond,Gerald B, PY - 2010/1/1/entrez PY - 2010/1/1/pubmed PY - 2010/3/31/medline SP - 916 EP - 7 JF - Journal of the American Chemical Society JO - J Am Chem Soc VL - 132 IS - 3 N2 - An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven-membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process. SN - 1520-5126 UR - https://www.unboundmedicine.com/medline/citation/20041710/Highly_efficient_Cu_I__catalyzed_synthesis_of_N_heterocycles_through_a_cyclization_triggered_addition_of_alkynes_ L2 - https://doi.org/10.1021/ja908883n DB - PRIME DP - Unbound Medicine ER -