Tags

Type your tag names separated by a space and hit enter

Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer.
Am J Epidemiol 2010; 171(4):436-46AJ

Abstract

The authors examined the association between the intake of different dairy products and the risk of bladder cancer in 120,852 men and women aged 55-69 years participating in the Netherlands Cohort Study on Diet and Cancer. Dairy product intake was assessed in 1986 by using a 150-item food frequency questionnaire. The cohort was followed for 16.3 years, and 1,549 incident cases of bladder cancer were analyzed. Cox proportional hazards analysis was applied with a case-cohort approach by using the follow-up data of a random subcohort (n = 5,000). Multivariate hazard ratio estimates comparing the highest with the lowest quintile of total dairy intake were 1.01 (95% confidence interval (CI): 0.81, 1.27; P(trend) = 0.68). A statistically significant association for fermented milk products was found only for the second quintile (median, 12 g/day) (hazard ratio = 0.71, 95% CI: 0.56, 0.91). Compared with nonconsumers, women with 25-75 g/day of butter consumption had a hazard ratio of 1.61 (95% CI: 1.03, 2.50; P(trend) < 0.01). No association was found with cheese, calcium, lactose, or nonfermented dairy intake. These results provide weak evidence that bladder cancer risk is inversely associated with low intake of fermented dairy products and suggest a positive association with butter intake in women.

Authors+Show Affiliations

Department of Epidemiology, Maastricht University, Maastricht, the Netherlands. andras.keszei@epid.unimaas.nlNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20042437

Citation

Keszei, András P., et al. "Dairy Intake and the Risk of Bladder Cancer in the Netherlands Cohort Study On Diet and Cancer." American Journal of Epidemiology, vol. 171, no. 4, 2010, pp. 436-46.
Keszei AP, Schouten LJ, Goldbohm RA, et al. Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer. Am J Epidemiol. 2010;171(4):436-46.
Keszei, A. P., Schouten, L. J., Goldbohm, R. A., & van den Brandt, P. A. (2010). Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer. American Journal of Epidemiology, 171(4), pp. 436-46. doi:10.1093/aje/kwp399.
Keszei AP, et al. Dairy Intake and the Risk of Bladder Cancer in the Netherlands Cohort Study On Diet and Cancer. Am J Epidemiol. 2010 Feb 15;171(4):436-46. PubMed PMID: 20042437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer. AU - Keszei,András P, AU - Schouten,Leo J, AU - Goldbohm,R Alexandra, AU - van den Brandt,Piet A, Y1 - 2009/12/30/ PY - 2010/1/1/entrez PY - 2010/1/1/pubmed PY - 2010/2/26/medline SP - 436 EP - 46 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 171 IS - 4 N2 - The authors examined the association between the intake of different dairy products and the risk of bladder cancer in 120,852 men and women aged 55-69 years participating in the Netherlands Cohort Study on Diet and Cancer. Dairy product intake was assessed in 1986 by using a 150-item food frequency questionnaire. The cohort was followed for 16.3 years, and 1,549 incident cases of bladder cancer were analyzed. Cox proportional hazards analysis was applied with a case-cohort approach by using the follow-up data of a random subcohort (n = 5,000). Multivariate hazard ratio estimates comparing the highest with the lowest quintile of total dairy intake were 1.01 (95% confidence interval (CI): 0.81, 1.27; P(trend) = 0.68). A statistically significant association for fermented milk products was found only for the second quintile (median, 12 g/day) (hazard ratio = 0.71, 95% CI: 0.56, 0.91). Compared with nonconsumers, women with 25-75 g/day of butter consumption had a hazard ratio of 1.61 (95% CI: 1.03, 2.50; P(trend) < 0.01). No association was found with cheese, calcium, lactose, or nonfermented dairy intake. These results provide weak evidence that bladder cancer risk is inversely associated with low intake of fermented dairy products and suggest a positive association with butter intake in women. SN - 1476-6256 UR - https://www.unboundmedicine.com/medline/citation/20042437/Dairy_intake_and_the_risk_of_bladder_cancer_in_the_Netherlands_Cohort_Study_on_Diet_and_Cancer_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwp399 DB - PRIME DP - Unbound Medicine ER -