Tags

Type your tag names separated by a space and hit enter

Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient.
J Heart Lung Transplant. 2010 May; 29(5):582-4.JH

Abstract

The novel 2009 H1N1 influenza virus has been reported to have increased severity in patients with underlying cardiovascular and lung disease. Pediatric patients also appear to have an increased incidence of infection. The impact on cardiothoracic transplant recipients, especially in pediatric recipients, has not been established. We report the case of a 12-year-old boy with history of congenital heart disease who was transplanted in June 2001. In October 2009, it was found that he had developed severe acute respiratory distress syndrome (ARDS) secondary to novel 2009 H1N1 influenza virus. Extracorporeal membrane oxygenation (ECMO) was given as support. Importantly, the initial specimen evaluated by real-time reverse transcriptase-polymerase chain reaction was negative for novel 2009 H1N1 influenza virus. The patient was successfully weaned from ECMO after 24 days, extubated at 6 weeks, and continues to make steady rehabilitative progress. Early suspicion for infection and initiation of treatment, even with negative testing, is essential for cardiothoracic transplant recipients during the current pandemic of novel 2009 H1N1 influenza virus.

Links

Publisher Full Text
Aggregator Full Text

Authors+Show Affiliations

Flagg A
Department of Pediatric Infectious Diseases, Cleveland Clinic Children's Hospital, Cleveland, Ohio 44195, USA.
Danziger-Isakov L
No affiliation info available
Foster C
No affiliation info available
Nasman C
No affiliation info available
Smedira N
No affiliation info available
Carl J
No affiliation info available
Kwon C
No affiliation info available
Davis S
No affiliation info available
Boyle G
No affiliation info available

MeSH

Antiviral AgentsChildCombined Modality TherapyExtracorporeal Membrane OxygenationHeart TransplantationHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanIntensive Care Units, PediatricMaleOpportunistic InfectionsOseltamivirPostoperative ComplicationsRespiratory Distress Syndrome

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20044274

Citation

Flagg, Aron, et al. "Novel 2009 H1N1 Influenza Virus Infection Requiring Extracorporeal Membrane Oxygenation in a Pediatric Heart Transplant Recipient." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation, vol. 29, no. 5, 2010, pp. 582-4.
Flagg A, Danziger-Isakov L, Foster C, et al. Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient. J Heart Lung Transplant. 2010;29(5):582-4.
Flagg, A., Danziger-Isakov, L., Foster, C., Nasman, C., Smedira, N., Carl, J., Kwon, C., Davis, S., & Boyle, G. (2010). Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation, 29(5), 582-4. https://doi.org/10.1016/j.healun.2009.11.600
Flagg A, et al. Novel 2009 H1N1 Influenza Virus Infection Requiring Extracorporeal Membrane Oxygenation in a Pediatric Heart Transplant Recipient. J Heart Lung Transplant. 2010;29(5):582-4. PubMed PMID: 20044274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient. AU - Flagg,Aron, AU - Danziger-Isakov,Lara, AU - Foster,Charles, AU - Nasman,Colleen, AU - Smedira,Nicholas, AU - Carl,John, AU - Kwon,Charles, AU - Davis,Stephen, AU - Boyle,Gerard, Y1 - 2009/12/31/ PY - 2009/10/30/received PY - 2009/11/20/revised PY - 2009/11/21/accepted PY - 2010/1/2/entrez PY - 2010/1/2/pubmed PY - 2010/7/27/medline SP - 582 EP - 4 JF - The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation JO - J Heart Lung Transplant VL - 29 IS - 5 N2 - The novel 2009 H1N1 influenza virus has been reported to have increased severity in patients with underlying cardiovascular and lung disease. Pediatric patients also appear to have an increased incidence of infection. The impact on cardiothoracic transplant recipients, especially in pediatric recipients, has not been established. We report the case of a 12-year-old boy with history of congenital heart disease who was transplanted in June 2001. In October 2009, it was found that he had developed severe acute respiratory distress syndrome (ARDS) secondary to novel 2009 H1N1 influenza virus. Extracorporeal membrane oxygenation (ECMO) was given as support. Importantly, the initial specimen evaluated by real-time reverse transcriptase-polymerase chain reaction was negative for novel 2009 H1N1 influenza virus. The patient was successfully weaned from ECMO after 24 days, extubated at 6 weeks, and continues to make steady rehabilitative progress. Early suspicion for infection and initiation of treatment, even with negative testing, is essential for cardiothoracic transplant recipients during the current pandemic of novel 2009 H1N1 influenza virus. SN - 1557-3117 UR - https://www.unboundmedicine.com/medline/citation/20044274/Novel_2009_H1N1_influenza_virus_infection_requiring_extracorporeal_membrane_oxygenation_in_a_pediatric_heart_transplant_recipient_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1053-2498(09)01504-6 DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓3]

Related Citations

More