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A study of 17 patients affected with plexiform neurofibromas in upper and lower extremities: comparison between different surgical techniques.
Acta Chir Plast. 2009; 51(2):35-40.AC

Abstract

Plexiform neurofibromas (PN) are one of the most common and severe types of neurofibroma that occur in neurofibromatosis type I. These tumours affect long portions of nerves, infiltrating the nerve and surrounding tissue thus causing significant pain, deformity and functional problems in the affected part of the body. Treatment of this variant of neurofibromas is currently surgical. The aim of this study was to analyze the surgical treatment of plexiform neurofibromas in the lower and upper extremities. The clinical pathological features of 29 neurofibromas, 12 in the upper extremities and 17 in the lower extremities, as diagnosed at the Department of Plastic and Reconstructive Surgery of University "La Sapienza" in Rome from 2000 to 2007, were reviewed. We established that subtotal and total resection without functional destruction is often possible for superficial PN.

Authors+Show Affiliations

Department of Dermatology and Plastic Reconstructive Surgery, University of Rome "Sapienza", Rome, Italy. mariagiuseppina.onesti@uniroma1.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

20050419

Citation

Onesti, M G., et al. "A Study of 17 Patients Affected With Plexiform Neurofibromas in Upper and Lower Extremities: Comparison Between Different Surgical Techniques." Acta Chirurgiae Plasticae, vol. 51, no. 2, 2009, pp. 35-40.
Onesti MG, Carella S, Spinelli G, et al. A study of 17 patients affected with plexiform neurofibromas in upper and lower extremities: comparison between different surgical techniques. Acta Chir Plast. 2009;51(2):35-40.
Onesti, M. G., Carella, S., Spinelli, G., Martano, A., Giustini, S., & Scuderi, N. (2009). A study of 17 patients affected with plexiform neurofibromas in upper and lower extremities: comparison between different surgical techniques. Acta Chirurgiae Plasticae, 51(2), 35-40.
Onesti MG, et al. A Study of 17 Patients Affected With Plexiform Neurofibromas in Upper and Lower Extremities: Comparison Between Different Surgical Techniques. Acta Chir Plast. 2009;51(2):35-40. PubMed PMID: 20050419.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A study of 17 patients affected with plexiform neurofibromas in upper and lower extremities: comparison between different surgical techniques. AU - Onesti,M G, AU - Carella,S, AU - Spinelli,G, AU - Martano,A, AU - Giustini,S, AU - Scuderi,N, PY - 2010/1/7/entrez PY - 2010/1/7/pubmed PY - 2010/2/19/medline SP - 35 EP - 40 JF - Acta chirurgiae plasticae JO - Acta Chir Plast VL - 51 IS - 2 N2 - Plexiform neurofibromas (PN) are one of the most common and severe types of neurofibroma that occur in neurofibromatosis type I. These tumours affect long portions of nerves, infiltrating the nerve and surrounding tissue thus causing significant pain, deformity and functional problems in the affected part of the body. Treatment of this variant of neurofibromas is currently surgical. The aim of this study was to analyze the surgical treatment of plexiform neurofibromas in the lower and upper extremities. The clinical pathological features of 29 neurofibromas, 12 in the upper extremities and 17 in the lower extremities, as diagnosed at the Department of Plastic and Reconstructive Surgery of University "La Sapienza" in Rome from 2000 to 2007, were reviewed. We established that subtotal and total resection without functional destruction is often possible for superficial PN. SN - 0001-5423 UR - https://www.unboundmedicine.com/medline/citation/20050419/A_study_of_17_patients_affected_with_plexiform_neurofibromas_in_upper_and_lower_extremities:_comparison_between_different_surgical_techniques_ L2 - https://medlineplus.gov/surgery.html DB - PRIME DP - Unbound Medicine ER -