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Alcohol consumption and risk of cardiovascular disease among hypertensive women.
Eur J Cardiovasc Prev Rehabil. 2010 Feb; 17(1):119-26.EJ

Abstract

AIM

This study investigated the relation between alcohol consumption and the risk of cardiovascular disease (CVD) among 10 530-hypertensive women from the EPIC-NL cohort.

METHODS AND RESULTS

Alcohol consumption was assessed using a validated food-frequency questionnaire and participants were followed for occurrence of CVD. During 9.4 years follow-up, we documented 580 coronary heart disease (CHD) events and 254 strokes, 165 of which were ischemic. An inverse association (Ptrend=0.009) between alcohol consumption and risk of CHD was observed with a multivariate-adjusted hazard ratio of 0.72 (95% confidence interval: 0.52-1.01) for those consuming 70-139.9 g alcohol/week compared to lifetime abstainers. Of different beverages, only red wine consumption was associated with a reduced risk of CHD. A U-shaped relation (P=0.08) was observed for total stroke with a hazard ratio of 0.65 (0.44-0.95) for consuming 5-69.9 g alcohol/week compared with lifetime abstainers. Similar results were observed for ischemic stroke with a hazard ratio of 0.56 (0.35-0.89) for consuming of 5-69.9 g alcohol/week.

CONCLUSION

We conclude that moderate alcohol consumption is associated with a reduced risk of CHD among hypertensive women. Light alcohol consumption tended to be related to a lower risk of stroke. Current guidelines for alcohol consumption in the general population also apply to hypertensive women.

Authors+Show Affiliations

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht , The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20051869

Citation

Bos, Sarah, et al. "Alcohol Consumption and Risk of Cardiovascular Disease Among Hypertensive Women." European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, vol. 17, no. 1, 2010, pp. 119-26.
Bos S, Grobbee DE, Boer JM, et al. Alcohol consumption and risk of cardiovascular disease among hypertensive women. Eur J Cardiovasc Prev Rehabil. 2010;17(1):119-26.
Bos, S., Grobbee, D. E., Boer, J. M., Verschuren, W. M., & Beulens, J. W. (2010). Alcohol consumption and risk of cardiovascular disease among hypertensive women. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 17(1), 119-26. https://doi.org/10.1097/HJR.0b013e328335f2fa
Bos S, et al. Alcohol Consumption and Risk of Cardiovascular Disease Among Hypertensive Women. Eur J Cardiovasc Prev Rehabil. 2010;17(1):119-26. PubMed PMID: 20051869.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and risk of cardiovascular disease among hypertensive women. AU - Bos,Sarah, AU - Grobbee,Diederick E, AU - Boer,Jolanda M A, AU - Verschuren,W Monique, AU - Beulens,Joline W J, PY - 2010/1/7/entrez PY - 2010/1/7/pubmed PY - 2010/4/28/medline SP - 119 EP - 26 JF - European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology JO - Eur J Cardiovasc Prev Rehabil VL - 17 IS - 1 N2 - AIM: This study investigated the relation between alcohol consumption and the risk of cardiovascular disease (CVD) among 10 530-hypertensive women from the EPIC-NL cohort. METHODS AND RESULTS: Alcohol consumption was assessed using a validated food-frequency questionnaire and participants were followed for occurrence of CVD. During 9.4 years follow-up, we documented 580 coronary heart disease (CHD) events and 254 strokes, 165 of which were ischemic. An inverse association (Ptrend=0.009) between alcohol consumption and risk of CHD was observed with a multivariate-adjusted hazard ratio of 0.72 (95% confidence interval: 0.52-1.01) for those consuming 70-139.9 g alcohol/week compared to lifetime abstainers. Of different beverages, only red wine consumption was associated with a reduced risk of CHD. A U-shaped relation (P=0.08) was observed for total stroke with a hazard ratio of 0.65 (0.44-0.95) for consuming 5-69.9 g alcohol/week compared with lifetime abstainers. Similar results were observed for ischemic stroke with a hazard ratio of 0.56 (0.35-0.89) for consuming of 5-69.9 g alcohol/week. CONCLUSION: We conclude that moderate alcohol consumption is associated with a reduced risk of CHD among hypertensive women. Light alcohol consumption tended to be related to a lower risk of stroke. Current guidelines for alcohol consumption in the general population also apply to hypertensive women. SN - 1741-8275 UR - https://www.unboundmedicine.com/medline/citation/20051869/Alcohol_consumption_and_risk_of_cardiovascular_disease_among_hypertensive_women_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=20051869.ui DB - PRIME DP - Unbound Medicine ER -