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[A new trincallane derivative from Salacia hainanensis Chun et How].
Yao Xue Xue Bao. 2009 Oct; 44(10):1123-6.YX

Abstract

Chemical constituents of the roots and stem of Salacia hainanensis Chun et How were isolated and purified with column chromatography on silica gel, Sephadex LH-20 and preparative HPLC. Their structures were elucidated based on physicochemical and spectral spectroscopic analysis. Depending on the activities of anti-alpha-glucosidase and inhibiting AGEs (advanced glycation end products, AGEs) formation in vitro, nine compounds were identified as 26, 27-dihydroxy-7, 24-tirucalladien-3-one (1), abruslactone A (2), lupeol (3), 21alpha, 30-dihydroxy-D: A-friedooleanan-3-one (4), 15alpha-hydroxyfriedelan-3-one (5), friedelin (6), mangiferin (7), epicatechin (8) and beta-sitosterol (9), separately. Among them, compound 1 is a new compound, and compound 2 was isolated from the Salacia genus for the first time, while, compounds 3, 4, 5, 8 were obtained from this plant for the first time.

Authors+Show Affiliations

Guo ZH
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xi RG
No affiliation info available
Wang XB
No affiliation info available
Wu LJ
No affiliation info available
Gao HY
No affiliation info available

MeSH

CatechinMolecular StructurePentacyclic TriterpenesPlant RootsPlant StemsPlants, MedicinalSalaciaSteroidsTriterpenesXanthones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

20055135

Citation

Guo, Zheng-Hong, et al. "[A New Trincallane Derivative From Salacia Hainanensis Chun Et How]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 44, no. 10, 2009, pp. 1123-6.
Guo ZH, Xi RG, Wang XB, et al. [A new trincallane derivative from Salacia hainanensis Chun et How]. Yao Xue Xue Bao. 2009;44(10):1123-6.
Guo, Z. H., Xi, R. G., Wang, X. B., Wu, L. J., & Gao, H. Y. (2009). [A new trincallane derivative from Salacia hainanensis Chun et How]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 44(10), 1123-6.
Guo ZH, et al. [A New Trincallane Derivative From Salacia Hainanensis Chun Et How]. Yao Xue Xue Bao. 2009;44(10):1123-6. PubMed PMID: 20055135.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A new trincallane derivative from Salacia hainanensis Chun et How]. AU - Guo,Zheng-Hong, AU - Xi,Rong-Gang, AU - Wang,Xiao-Bo, AU - Wu,Li-Jun, AU - Gao,Hui-Yuan, PY - 2010/1/9/entrez PY - 2010/1/9/pubmed PY - 2012/7/24/medline SP - 1123 EP - 6 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 44 IS - 10 N2 - Chemical constituents of the roots and stem of Salacia hainanensis Chun et How were isolated and purified with column chromatography on silica gel, Sephadex LH-20 and preparative HPLC. Their structures were elucidated based on physicochemical and spectral spectroscopic analysis. Depending on the activities of anti-alpha-glucosidase and inhibiting AGEs (advanced glycation end products, AGEs) formation in vitro, nine compounds were identified as 26, 27-dihydroxy-7, 24-tirucalladien-3-one (1), abruslactone A (2), lupeol (3), 21alpha, 30-dihydroxy-D: A-friedooleanan-3-one (4), 15alpha-hydroxyfriedelan-3-one (5), friedelin (6), mangiferin (7), epicatechin (8) and beta-sitosterol (9), separately. Among them, compound 1 is a new compound, and compound 2 was isolated from the Salacia genus for the first time, while, compounds 3, 4, 5, 8 were obtained from this plant for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/20055135/[A_new_trincallane_derivative_from_Salacia_hainanensis_Chun_et_How]_ DB - PRIME DP - Unbound Medicine ER -