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[Research progress of neuraminidase inhibitors for anti-influenza].
Yao Xue Xue Bao. 2009 Sep; 44(9):935-42.YX

Abstract

Influenza is a global contagious disease, which causes hundreds of thousands of people deaths. And new subtype of influenza may cause pandemic influenza, and lead to more serious consequence. Drugs for anti-influenza have played very important roles in influenza treatment and prevention, especially neuraminidase inhibitors are effective on both influenza A and B which have more safety and tolerance, therefore they have been widely used for influenza treatment. However, several viral drug-resistant cases have been reported. In this paper, the clinic therapy, prevention and drug resistance of neuraminidase inhibitors, including zanamivir, oseltamivir and peramivir, and progress in the research and development in our country are presented in order to promote research and development of new drugs for influenza treatment and prevention.

Authors+Show Affiliations

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Review

Language

chi

PubMed ID

20055166

Citation

Liu, Ai-Lin, et al. "[Research Progress of Neuraminidase Inhibitors for Anti-influenza]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 44, no. 9, 2009, pp. 935-42.
Liu AL, Wang HD, Yang F, et al. [Research progress of neuraminidase inhibitors for anti-influenza]. Yao Xue Xue Bao. 2009;44(9):935-42.
Liu, A. L., Wang, H. D., Yang, F., & Du, G. H. (2009). [Research progress of neuraminidase inhibitors for anti-influenza]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 44(9), 935-42.
Liu AL, et al. [Research Progress of Neuraminidase Inhibitors for Anti-influenza]. Yao Xue Xue Bao. 2009;44(9):935-42. PubMed PMID: 20055166.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Research progress of neuraminidase inhibitors for anti-influenza]. AU - Liu,Ai-Lin, AU - Wang,Hai-Di, AU - Yang,Fan, AU - Du,Guan-Hua, PY - 2010/1/9/entrez PY - 2010/1/9/pubmed PY - 2012/12/21/medline SP - 935 EP - 42 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 44 IS - 9 N2 - Influenza is a global contagious disease, which causes hundreds of thousands of people deaths. And new subtype of influenza may cause pandemic influenza, and lead to more serious consequence. Drugs for anti-influenza have played very important roles in influenza treatment and prevention, especially neuraminidase inhibitors are effective on both influenza A and B which have more safety and tolerance, therefore they have been widely used for influenza treatment. However, several viral drug-resistant cases have been reported. In this paper, the clinic therapy, prevention and drug resistance of neuraminidase inhibitors, including zanamivir, oseltamivir and peramivir, and progress in the research and development in our country are presented in order to promote research and development of new drugs for influenza treatment and prevention. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/20055166/[Research_progress_of_neuraminidase_inhibitors_for_anti_influenza]_ DB - PRIME DP - Unbound Medicine ER -