Tags

Type your tag names separated by a space and hit enter

Maternal polycystic ovary syndrome may be associated with adverse pregnancy outcomes.

Abstract

OBJECTIVE

To determine whether maternal polycystic ovary syndrome (PCOS) is associated with adverse pregnancy outcomes in a population of Italian parturients.

STUDY DESIGN

Retrospective study carried out in an academic hospital in Bologna, Italy, including 516 consecutive Italian women who delivered between January and April 2006. PCOS women, women with hyperandrogenic features not configuring PCOS (Intermediate group) and non-hyperandrogenic controls were identified by a telephone survey of 229 women. Statistical analysis was performed using ANOVA or chi-square.

RESULTS

PCOS women, accounted for 6.6% of our cohort. Gestational diabetes mellitus (GDM) was significantly more frequent in the PCOS group than in the other groups (20% vs. 3.6% and 4%; P<0.01). The association of GDM and pregnancy-induced hypertension occurred in one subject in the PCOS group but in none of the other groups (P<0.001). Preterm birth was more frequent in the PCOS group than in control group (20% vs. 6.9%; P<0.05), whereas mean length of gestation was not different. The higher occurrence of adverse outcomes may be, at least partly, related to a higher weight gain during pregnancy in PCOS group with respect to the other groups (P<0.05).

CONCLUSIONS

Women affected by PCOS carry an increased risk of adverse pregnancy outcomes.

Authors+Show Affiliations

Division of Endocrinology, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, via Massarenti 9, 40138 Bologna, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20056308

Citation

Altieri, Paola, et al. "Maternal Polycystic Ovary Syndrome May Be Associated With Adverse Pregnancy Outcomes." European Journal of Obstetrics, Gynecology, and Reproductive Biology, vol. 149, no. 1, 2010, pp. 31-6.
Altieri P, Gambineri A, Prontera O, et al. Maternal polycystic ovary syndrome may be associated with adverse pregnancy outcomes. Eur J Obstet Gynecol Reprod Biol. 2010;149(1):31-6.
Altieri, P., Gambineri, A., Prontera, O., Cionci, G., Franchina, M., & Pasquali, R. (2010). Maternal polycystic ovary syndrome may be associated with adverse pregnancy outcomes. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 149(1), pp. 31-6. doi:10.1016/j.ejogrb.2009.11.010.
Altieri P, et al. Maternal Polycystic Ovary Syndrome May Be Associated With Adverse Pregnancy Outcomes. Eur J Obstet Gynecol Reprod Biol. 2010;149(1):31-6. PubMed PMID: 20056308.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Maternal polycystic ovary syndrome may be associated with adverse pregnancy outcomes. AU - Altieri,Paola, AU - Gambineri,Alessandra, AU - Prontera,Olga, AU - Cionci,Gianluca, AU - Franchina,Michele, AU - Pasquali,Renato, Y1 - 2010/01/06/ PY - 2009/03/06/received PY - 2009/10/02/revised PY - 2009/11/16/accepted PY - 2010/1/9/entrez PY - 2010/1/9/pubmed PY - 2010/5/4/medline SP - 31 EP - 6 JF - European journal of obstetrics, gynecology, and reproductive biology JO - Eur. J. Obstet. Gynecol. Reprod. Biol. VL - 149 IS - 1 N2 - OBJECTIVE: To determine whether maternal polycystic ovary syndrome (PCOS) is associated with adverse pregnancy outcomes in a population of Italian parturients. STUDY DESIGN: Retrospective study carried out in an academic hospital in Bologna, Italy, including 516 consecutive Italian women who delivered between January and April 2006. PCOS women, women with hyperandrogenic features not configuring PCOS (Intermediate group) and non-hyperandrogenic controls were identified by a telephone survey of 229 women. Statistical analysis was performed using ANOVA or chi-square. RESULTS: PCOS women, accounted for 6.6% of our cohort. Gestational diabetes mellitus (GDM) was significantly more frequent in the PCOS group than in the other groups (20% vs. 3.6% and 4%; P<0.01). The association of GDM and pregnancy-induced hypertension occurred in one subject in the PCOS group but in none of the other groups (P<0.001). Preterm birth was more frequent in the PCOS group than in control group (20% vs. 6.9%; P<0.05), whereas mean length of gestation was not different. The higher occurrence of adverse outcomes may be, at least partly, related to a higher weight gain during pregnancy in PCOS group with respect to the other groups (P<0.05). CONCLUSIONS: Women affected by PCOS carry an increased risk of adverse pregnancy outcomes. SN - 1872-7654 UR - https://www.unboundmedicine.com/medline/citation/20056308/Maternal_polycystic_ovary_syndrome_may_be_associated_with_adverse_pregnancy_outcomes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0301-2115(09)00685-X DB - PRIME DP - Unbound Medicine ER -