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[Epidemiology of Alzheimer's disease: methodological approaches and new perspectives].
Psychol Neuropsychiatr Vieil 2009; 7 Spec No 1:7-14PN

Abstract

Over the last 20 years, a number of epidemiological studies on Alzheimer's disease (AD) have been conducted on large cohorts providing databases for studying the disease frequency, and leading to a more global overview of AD risk factors. However, precise identification of factors which potentiate or delay the pathological process of the disease is still incomplete. One of the major problems comes from difficulties for defining the cases and obtaining good clinical diagnoses in population-based studies. Moreover, it is difficult to determine the chronology of exposure-disease relationships whatever the factors studied: vascular factors, life habits (dietary habits, physical, social or intellectual activities...). Which life-course period is important for proposing interventions to modify these factors remains a central question. The longer follow-up of large cohorts and a better knowledge of potential risk factors constitute a research priority if we want to prevent efficiently AD in the near future.

Authors+Show Affiliations

Inserm U888, Université Montpellier 1, Paris.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

20061228

Citation

Berr, Claudine, et al. "[Epidemiology of Alzheimer's Disease: Methodological Approaches and New Perspectives]." Psychologie & Neuropsychiatrie Du Vieillissement, vol. 7 Spec No 1, 2009, pp. 7-14.
Berr C, Vercambre MN, Akbaraly TN. [Epidemiology of Alzheimer's disease: methodological approaches and new perspectives]. Psychol Neuropsychiatr Vieil. 2009;7 Spec No 1:7-14.
Berr, C., Vercambre, M. N., & Akbaraly, T. N. (2009). [Epidemiology of Alzheimer's disease: methodological approaches and new perspectives]. Psychologie & Neuropsychiatrie Du Vieillissement, 7 Spec No 1, pp. 7-14. doi:10.1684/pnv.2009.0191.
Berr C, Vercambre MN, Akbaraly TN. [Epidemiology of Alzheimer's Disease: Methodological Approaches and New Perspectives]. Psychol Neuropsychiatr Vieil. 2009;7 Spec No 1:7-14. PubMed PMID: 20061228.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Epidemiology of Alzheimer's disease: methodological approaches and new perspectives]. AU - Berr,Claudine, AU - Vercambre,Marie-Noël, AU - Akbaraly,Tasnime Nassime, PY - 2010/1/12/entrez PY - 2010/3/6/pubmed PY - 2010/4/1/medline SP - 7 EP - 14 JF - Psychologie & neuropsychiatrie du vieillissement JO - Psychol Neuropsychiatr Vieil VL - 7 Spec No 1 N2 - Over the last 20 years, a number of epidemiological studies on Alzheimer's disease (AD) have been conducted on large cohorts providing databases for studying the disease frequency, and leading to a more global overview of AD risk factors. However, precise identification of factors which potentiate or delay the pathological process of the disease is still incomplete. One of the major problems comes from difficulties for defining the cases and obtaining good clinical diagnoses in population-based studies. Moreover, it is difficult to determine the chronology of exposure-disease relationships whatever the factors studied: vascular factors, life habits (dietary habits, physical, social or intellectual activities...). Which life-course period is important for proposing interventions to modify these factors remains a central question. The longer follow-up of large cohorts and a better knowledge of potential risk factors constitute a research priority if we want to prevent efficiently AD in the near future. SN - 1760-1703 UR - https://www.unboundmedicine.com/medline/citation/20061228/[Epidemiology_of_Alzheimer's_disease:_methodological_approaches_and_new_perspectives]_ L2 - http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2009.0191 DB - PRIME DP - Unbound Medicine ER -