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Bioavailability of various polyphenols from a diet containing moderate amounts of berries.
J Agric Food Chem. 2010 Apr 14; 58(7):3927-32.JA

Abstract

Berries are a rich source of various polyphenols. The objective of this study was to investigate the bioavailability of polyphenols from berries. Middle-aged subjects (n = 72) consumed moderate amounts of berry or control products for 8 weeks in a randomized, placebo-controlled dietary intervention trial. Average intake of berries was 160 g/day (bilberries, lingonberries, black currants, and chokeberries). Plasma and urine polyphenols were analyzed by GC-MS and HPLC and berry polyphenols by HPLC. The total intake of polyphenols was 837 mg/day. Plasma quercetin, p-coumaric acid, 3-hydroxyphenylacetic acid, caffeic acid, protocatechuic acid, vanillic acid, homovanillic acid, and 3-(3-hydroxyphenyl)propionic acid increased significantly from the baseline in the berry group compared to the control group (p < 0.05). The urinary excretion of quercetin, p-coumaric acid, and 3-hydroxyphenylacetic acid increased significantly in the berry group compared to the control group (p < 0.05). In conclusion, a number of polyphenols are bioavailable from a diet containing moderate amounts of blue and red berries.

Authors+Show Affiliations

Disease Risk Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare (THL), Helsinki, Finland. raika.koli@thl.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20073463

Citation

Koli, Raika, et al. "Bioavailability of Various Polyphenols From a Diet Containing Moderate Amounts of Berries." Journal of Agricultural and Food Chemistry, vol. 58, no. 7, 2010, pp. 3927-32.
Koli R, Erlund I, Jula A, et al. Bioavailability of various polyphenols from a diet containing moderate amounts of berries. J Agric Food Chem. 2010;58(7):3927-32.
Koli, R., Erlund, I., Jula, A., Marniemi, J., Mattila, P., & Alfthan, G. (2010). Bioavailability of various polyphenols from a diet containing moderate amounts of berries. Journal of Agricultural and Food Chemistry, 58(7), 3927-32. https://doi.org/10.1021/jf9024823
Koli R, et al. Bioavailability of Various Polyphenols From a Diet Containing Moderate Amounts of Berries. J Agric Food Chem. 2010 Apr 14;58(7):3927-32. PubMed PMID: 20073463.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bioavailability of various polyphenols from a diet containing moderate amounts of berries. AU - Koli,Raika, AU - Erlund,Iris, AU - Jula,Antti, AU - Marniemi,Jukka, AU - Mattila,Pirjo, AU - Alfthan,Georg, PY - 2010/1/16/entrez PY - 2010/1/16/pubmed PY - 2010/9/2/medline SP - 3927 EP - 32 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 58 IS - 7 N2 - Berries are a rich source of various polyphenols. The objective of this study was to investigate the bioavailability of polyphenols from berries. Middle-aged subjects (n = 72) consumed moderate amounts of berry or control products for 8 weeks in a randomized, placebo-controlled dietary intervention trial. Average intake of berries was 160 g/day (bilberries, lingonberries, black currants, and chokeberries). Plasma and urine polyphenols were analyzed by GC-MS and HPLC and berry polyphenols by HPLC. The total intake of polyphenols was 837 mg/day. Plasma quercetin, p-coumaric acid, 3-hydroxyphenylacetic acid, caffeic acid, protocatechuic acid, vanillic acid, homovanillic acid, and 3-(3-hydroxyphenyl)propionic acid increased significantly from the baseline in the berry group compared to the control group (p < 0.05). The urinary excretion of quercetin, p-coumaric acid, and 3-hydroxyphenylacetic acid increased significantly in the berry group compared to the control group (p < 0.05). In conclusion, a number of polyphenols are bioavailable from a diet containing moderate amounts of blue and red berries. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/20073463/Bioavailability_of_various_polyphenols_from_a_diet_containing_moderate_amounts_of_berries_ L2 - https://doi.org/10.1021/jf9024823 DB - PRIME DP - Unbound Medicine ER -