Abstract
PURPOSE
To evaluate the potential of stratus optical coherence tomography (OCT) for detecting early glaucoma.
PATIENTS AND METHODS
Fifty-two open-angle glaucoma patients with unilateral visual field loss detected by standard automatic perimetry were tested using stratus OCT and frequency doubling technology (FDT) N-30. Fifty-two perimetrically normal eyes were enrolled and divided into 2 groups: eyes with normal OCT results and eyes with abnormal OCT results. FDT parameters and scores were compared between the 2 groups. We evaluated the topographic relationship of the OCT-measured retinal nerve fiber layer (RNFL) defects with the FDT-measured visual field loss and glaucomatous optic neuropathy.
RESULTS
In eyes with abnormal OCT results, the percentage of eyes with abnormal FDT results was significantly higher (P<0.001); FDT mean deviation, pattern standard deviation, and scores were significantly worse than those with normal OCT results (P=0.005, P<0.001, P<0.001, respectively); and the OCT-measured RNFL defects showed good topographic agreement with the FDT-measured visual field loss and glaucomatous optic neuropathy.
CONCLUSIONS
RNFL defects detected by stratus OCT were associated with FDT visual field loss. Stratus OCT can detect early glaucoma sooner than standard automatic perimetry.
TY - JOUR
T1 - Potential of stratus optical coherence tomography for detecting early glaucoma in perimetrically normal eyes of open-angle glaucoma patients with unilateral visual field loss.
AU - Zhang,Yu,
AU - Wu,Ling-Ling,
AU - Yang,Yan-Fang,
PY - 2010/1/16/entrez
PY - 2010/1/16/pubmed
PY - 2010/3/20/medline
SP - 61
EP - 5
JF - Journal of glaucoma
JO - J Glaucoma
VL - 19
IS - 1
N2 - PURPOSE: To evaluate the potential of stratus optical coherence tomography (OCT) for detecting early glaucoma. PATIENTS AND METHODS: Fifty-two open-angle glaucoma patients with unilateral visual field loss detected by standard automatic perimetry were tested using stratus OCT and frequency doubling technology (FDT) N-30. Fifty-two perimetrically normal eyes were enrolled and divided into 2 groups: eyes with normal OCT results and eyes with abnormal OCT results. FDT parameters and scores were compared between the 2 groups. We evaluated the topographic relationship of the OCT-measured retinal nerve fiber layer (RNFL) defects with the FDT-measured visual field loss and glaucomatous optic neuropathy. RESULTS: In eyes with abnormal OCT results, the percentage of eyes with abnormal FDT results was significantly higher (P<0.001); FDT mean deviation, pattern standard deviation, and scores were significantly worse than those with normal OCT results (P=0.005, P<0.001, P<0.001, respectively); and the OCT-measured RNFL defects showed good topographic agreement with the FDT-measured visual field loss and glaucomatous optic neuropathy. CONCLUSIONS: RNFL defects detected by stratus OCT were associated with FDT visual field loss. Stratus OCT can detect early glaucoma sooner than standard automatic perimetry.
SN - 1536-481X
UR - https://www.unboundmedicine.com/medline/citation/20075675/Potential_of_stratus_optical_coherence_tomography_for_detecting_early_glaucoma_in_perimetrically_normal_eyes_of_open_angle_glaucoma_patients_with_unilateral_visual_field_loss_
L2 - https://doi.org/10.1097/IJG.0b013e31819c486b
DB - PRIME
DP - Unbound Medicine
ER -