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Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis.
Altern Ther Health Med. 2010 Jan-Feb; 16(1):36-44.AT

Abstract

This study aimed to review the evidence on the efficacy of herbal preparations containing black cohosh for the treatment of menopausal symptoms. A systematic search of three databases (PubMed, Embase, and Cochrane library) was conducted to identify relevant literature. Two reviewers independently abstracted the data from the eligible studies. Of the 288 English language citations screened, nine randomized placebo-controlled trials were included. Among these trials, six demonstrated a significant improvement in the black cohosh group compared with the placebo group. Using data from seven trials, we calculated a combined estimate for the change in menopausal vasomotor symptoms. Preparations containing black cohosh improved these symptoms overall by 26% (95% confidence interval 11%-40%); there was, however, significant heterogeneity between these trials. Given that black cohosh is one of the most frequently used herbal medications for menopausal vasomotor symptoms in North America, more data are warranted on its effectiveness and safety.

Authors+Show Affiliations

Department of Obstetrics, St. Mary's Hospital and McGill University, Montreal, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

20085176

Citation

Shams, Taghreed, et al. "Efficacy of Black Cohosh-containing Preparations On Menopausal Symptoms: a Meta-analysis." Alternative Therapies in Health and Medicine, vol. 16, no. 1, 2010, pp. 36-44.
Shams T, Setia MS, Hemmings R, et al. Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis. Altern Ther Health Med. 2010;16(1):36-44.
Shams, T., Setia, M. S., Hemmings, R., McCusker, J., Sewitch, M., & Ciampi, A. (2010). Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis. Alternative Therapies in Health and Medicine, 16(1), 36-44.
Shams T, et al. Efficacy of Black Cohosh-containing Preparations On Menopausal Symptoms: a Meta-analysis. Altern Ther Health Med. 2010 Jan-Feb;16(1):36-44. PubMed PMID: 20085176.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis. AU - Shams,Taghreed, AU - Setia,Maninder Singh, AU - Hemmings,Robert, AU - McCusker,Jane, AU - Sewitch,Maida, AU - Ciampi,Antonio, PY - 2010/1/21/entrez PY - 2010/1/21/pubmed PY - 2010/2/20/medline SP - 36 EP - 44 JF - Alternative therapies in health and medicine JO - Altern Ther Health Med VL - 16 IS - 1 N2 - This study aimed to review the evidence on the efficacy of herbal preparations containing black cohosh for the treatment of menopausal symptoms. A systematic search of three databases (PubMed, Embase, and Cochrane library) was conducted to identify relevant literature. Two reviewers independently abstracted the data from the eligible studies. Of the 288 English language citations screened, nine randomized placebo-controlled trials were included. Among these trials, six demonstrated a significant improvement in the black cohosh group compared with the placebo group. Using data from seven trials, we calculated a combined estimate for the change in menopausal vasomotor symptoms. Preparations containing black cohosh improved these symptoms overall by 26% (95% confidence interval 11%-40%); there was, however, significant heterogeneity between these trials. Given that black cohosh is one of the most frequently used herbal medications for menopausal vasomotor symptoms in North America, more data are warranted on its effectiveness and safety. SN - 1078-6791 UR - https://www.unboundmedicine.com/medline/citation/20085176/Efficacy_of_black_cohosh_containing_preparations_on_menopausal_symptoms:_a_meta_analysis_ L2 - https://medlineplus.gov/womenshealth.html DB - PRIME DP - Unbound Medicine ER -