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Effect of zinc supplementation on mood states in young women: a pilot study.
Eur J Clin Nutr. 2010 Mar; 64(3):331-3.EJ

Abstract

The relation of zinc (Zn) nutriture to brain development and function has been elucidated. The purpose of this study is to examine whether Zn supplementation improves mood states in young women. The study used a double-blind, randomized and placebo-controlled procedure. The major outcomes were psychological measures, somatic symptoms and serum Zn. Thirty women were placed randomly and in equal numbers into two groups, and they ingested one capsule containing multivitamins (MVs) or MV and 7 mg Zn daily for 10 weeks. Women who took MV and Zn showed a significant reduction in anger-hostility score (P=0.009) and depression-dejection score (P=0.011) in the Profile of Moods State (POMS) and a significant increase in serum Zn concentration (P=0.008), whereas women who took only MV did not. Our results suggest that Zn supplementation may be effective in reducing anger and depression.

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Authors+Show Affiliations

Sawada T
Department of Food and Nutrition, Morioka Daigaku Junior College, Iwate, Japan.
Yokoi K
No affiliation info available

MeSH

AdolescentAffectAngerDepressionDietary SupplementsDouble-Blind MethodFemaleHumansNutritional StatusPilot ProjectsPsychometricsTrace ElementsTreatment OutcomeVitaminsYoung AdultZinc

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20087376

Citation

Sawada, T, and K Yokoi. "Effect of Zinc Supplementation On Mood States in Young Women: a Pilot Study." European Journal of Clinical Nutrition, vol. 64, no. 3, 2010, pp. 331-3.
Sawada T, Yokoi K. Effect of zinc supplementation on mood states in young women: a pilot study. Eur J Clin Nutr. 2010;64(3):331-3.
Sawada, T., & Yokoi, K. (2010). Effect of zinc supplementation on mood states in young women: a pilot study. European Journal of Clinical Nutrition, 64(3), 331-3. https://doi.org/10.1038/ejcn.2009.158
Sawada T, Yokoi K. Effect of Zinc Supplementation On Mood States in Young Women: a Pilot Study. Eur J Clin Nutr. 2010;64(3):331-3. PubMed PMID: 20087376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of zinc supplementation on mood states in young women: a pilot study. AU - Sawada,T, AU - Yokoi,K, Y1 - 2010/01/20/ PY - 2010/1/21/entrez PY - 2010/1/21/pubmed PY - 2010/5/15/medline SP - 331 EP - 3 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 64 IS - 3 N2 - The relation of zinc (Zn) nutriture to brain development and function has been elucidated. The purpose of this study is to examine whether Zn supplementation improves mood states in young women. The study used a double-blind, randomized and placebo-controlled procedure. The major outcomes were psychological measures, somatic symptoms and serum Zn. Thirty women were placed randomly and in equal numbers into two groups, and they ingested one capsule containing multivitamins (MVs) or MV and 7 mg Zn daily for 10 weeks. Women who took MV and Zn showed a significant reduction in anger-hostility score (P=0.009) and depression-dejection score (P=0.011) in the Profile of Moods State (POMS) and a significant increase in serum Zn concentration (P=0.008), whereas women who took only MV did not. Our results suggest that Zn supplementation may be effective in reducing anger and depression. SN - 1476-5640 UR - https://www.unboundmedicine.com/medline/citation/20087376/Effect_of_zinc_supplementation_on_mood_states_in_young_women:_a_pilot_study_ L2 - https://doi.org/10.1038/ejcn.2009.158 DB - PRIME DP - Unbound Medicine ER -