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Narrowband ultraviolet B course improves vitamin D balance in women in winter.
Br J Dermatol. 2010 Apr; 162(4):848-53.BJ

Abstract

BACKGROUND

Vitamin D insufficiency is common in winter in the Nordic countries.

OBJECTIVES

To examine whether a short course of narrowband ultraviolet B (NB-UVB) improves vitamin D balance.

METHODS

Fifty-six healthy, white women (mean age 41 years) volunteered and 53 completed the study. NB-UVB exposures were given on seven consecutive days either on the whole body (n = 19), on the head and arms (n = 9) or on the abdomen (n = 14). Similarly, seven solar simulator exposures were given on the face and arms (n = 11). The cumulative UVB dose was 13 standard erythema doses in all regimens. Serum calcidiol (25-hydroxyvitamin D) concentration was measured by radioimmunoassay before and after the NB-UVB exposures. Follow-up samples were taken from the whole-body NB-UVB group at 2 months.

RESULTS

At onset 41 women (77%) had vitamin D insufficiency (calcidiol < 50 nmol L(-1)) and six (11%) had vitamin D deficiency (calcidiol < 25 nmol L(-1)). Calcidiol concentration increased significantly, by a mean of 11.4 nmol L(-1) when NB-UVB was given on the whole body, by 11.0 nmol L(-1) when given on the head and arms and by 4.0 nmol L(-1) when given on the abdomen. Solar simulator exposures given on the face and arms increased calcidiol by 3.8 nmol L(-1). After 2 months serum calcidiol was still higher than initially in the group who received NB-UVB exposures on the whole body.

CONCLUSIONS

NB-UVB exposures given on seven consecutive days on different skin areas of healthy women significantly improved serum calcidiol concentration. A short low-dose NB-UVB course can improve vitamin D balance in winter.

Authors+Show Affiliations

Department of Dermatology, Päijät-Häme Central Hospital, Lahti, Finland. katja.vahavihu@uta.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20105173

Citation

Vähävihu, K, et al. "Narrowband Ultraviolet B Course Improves Vitamin D Balance in Women in Winter." The British Journal of Dermatology, vol. 162, no. 4, 2010, pp. 848-53.
Vähävihu K, Ylianttila L, Kautiainen H, et al. Narrowband ultraviolet B course improves vitamin D balance in women in winter. Br J Dermatol. 2010;162(4):848-53.
Vähävihu, K., Ylianttila, L., Kautiainen, H., Viljakainen, H., Lamberg-Allardt, C., Hasan, T., Tuohimaa, P., Reunala, T., & Snellman, E. (2010). Narrowband ultraviolet B course improves vitamin D balance in women in winter. The British Journal of Dermatology, 162(4), 848-53. https://doi.org/10.1111/j.1365-2133.2010.09629.x
Vähävihu K, et al. Narrowband Ultraviolet B Course Improves Vitamin D Balance in Women in Winter. Br J Dermatol. 2010;162(4):848-53. PubMed PMID: 20105173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Narrowband ultraviolet B course improves vitamin D balance in women in winter. AU - Vähävihu,K, AU - Ylianttila,L, AU - Kautiainen,H, AU - Viljakainen,H, AU - Lamberg-Allardt,C, AU - Hasan,T, AU - Tuohimaa,P, AU - Reunala,T, AU - Snellman,E, Y1 - 2010/01/22/ PY - 2010/1/29/entrez PY - 2010/1/29/pubmed PY - 2010/10/7/medline SP - 848 EP - 53 JF - The British journal of dermatology JO - Br J Dermatol VL - 162 IS - 4 N2 - BACKGROUND: Vitamin D insufficiency is common in winter in the Nordic countries. OBJECTIVES: To examine whether a short course of narrowband ultraviolet B (NB-UVB) improves vitamin D balance. METHODS: Fifty-six healthy, white women (mean age 41 years) volunteered and 53 completed the study. NB-UVB exposures were given on seven consecutive days either on the whole body (n = 19), on the head and arms (n = 9) or on the abdomen (n = 14). Similarly, seven solar simulator exposures were given on the face and arms (n = 11). The cumulative UVB dose was 13 standard erythema doses in all regimens. Serum calcidiol (25-hydroxyvitamin D) concentration was measured by radioimmunoassay before and after the NB-UVB exposures. Follow-up samples were taken from the whole-body NB-UVB group at 2 months. RESULTS: At onset 41 women (77%) had vitamin D insufficiency (calcidiol < 50 nmol L(-1)) and six (11%) had vitamin D deficiency (calcidiol < 25 nmol L(-1)). Calcidiol concentration increased significantly, by a mean of 11.4 nmol L(-1) when NB-UVB was given on the whole body, by 11.0 nmol L(-1) when given on the head and arms and by 4.0 nmol L(-1) when given on the abdomen. Solar simulator exposures given on the face and arms increased calcidiol by 3.8 nmol L(-1). After 2 months serum calcidiol was still higher than initially in the group who received NB-UVB exposures on the whole body. CONCLUSIONS: NB-UVB exposures given on seven consecutive days on different skin areas of healthy women significantly improved serum calcidiol concentration. A short low-dose NB-UVB course can improve vitamin D balance in winter. SN - 1365-2133 UR - https://www.unboundmedicine.com/medline/citation/20105173/Narrowband_ultraviolet_B_course_improves_vitamin_D_balance_in_women_in_winter_ L2 - https://doi.org/10.1111/j.1365-2133.2010.09629.x DB - PRIME DP - Unbound Medicine ER -