Tags

Type your tag names separated by a space and hit enter

[Acne vulgaris. The role of hormones].
Hautarzt. 2010 Feb; 61(2):107-8, 110-4.H

Abstract

Peripherally active androgens control cellular functions by binding to androgen receptors. Follicular keratinocytes and sebocytes are target cells for androgens, which, directly or indirectly, stimulate keratinocyte proliferation and the volume of sebaceous glands as well as the sebum secretion rate. Acne often begins with the adrenarche, namely with the up- regulation of adrenal synthesis of dehydroepiandrosterone sulfate, a hormone that is upstream to testosterone. The majority of acne patients exhibit normal levels of circulating androgens, while sebaceous glands from acne regions exhibit a stronger sensitivity to androgens than the sebaceous glands from other parts of the body. Hormone-like active lipids, hormones in diet and neuropeptides may also play a role in the development of acne lesions. The target of antiandrogen treatment of the skin is mainly the sebaceous gland and the primary effect is sebostasis.

Authors+Show Affiliations

Klinik für Dermatologie, Venerologie und Allergologie/Immunologisches Zentrum, Städtisches Klinikum Dessau, Auenweg 38, 06847 Dessau-Rosslau. christos.zouboulis@klinikum-dessau.de

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

20107754

Citation

Zouboulis, C C.. "[Acne Vulgaris. the Role of Hormones]." Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, vol. 61, no. 2, 2010, pp. 107-8, 110-4.
Zouboulis CC. [Acne vulgaris. The role of hormones]. Hautarzt. 2010;61(2):107-8, 110-4.
Zouboulis, C. C. (2010). [Acne vulgaris. The role of hormones]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, 61(2), 107-8, 110-4. https://doi.org/10.1007/s00105-009-1830-1
Zouboulis CC. [Acne Vulgaris. the Role of Hormones]. Hautarzt. 2010;61(2):107-8, 110-4. PubMed PMID: 20107754.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Acne vulgaris. The role of hormones]. A1 - Zouboulis,C C, PY - 2010/1/29/entrez PY - 2010/1/29/pubmed PY - 2010/5/4/medline SP - 107-8, 110-4 JF - Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete JO - Hautarzt VL - 61 IS - 2 N2 - Peripherally active androgens control cellular functions by binding to androgen receptors. Follicular keratinocytes and sebocytes are target cells for androgens, which, directly or indirectly, stimulate keratinocyte proliferation and the volume of sebaceous glands as well as the sebum secretion rate. Acne often begins with the adrenarche, namely with the up- regulation of adrenal synthesis of dehydroepiandrosterone sulfate, a hormone that is upstream to testosterone. The majority of acne patients exhibit normal levels of circulating androgens, while sebaceous glands from acne regions exhibit a stronger sensitivity to androgens than the sebaceous glands from other parts of the body. Hormone-like active lipids, hormones in diet and neuropeptides may also play a role in the development of acne lesions. The target of antiandrogen treatment of the skin is mainly the sebaceous gland and the primary effect is sebostasis. SN - 1432-1173 UR - https://www.unboundmedicine.com/medline/citation/20107754/[Acne_vulgaris__The_role_of_hormones]_ L2 - https://dx.doi.org/10.1007/s00105-009-1830-1 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.