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Use of aripiprazole in clozapine induced enuresis: report of two cases.
J Korean Med Sci. 2010 Feb; 25(2):333-5.JK

Abstract

This report describes the efficacy of combined use of aripiprazole in the treatment of a patient with clozapine induced enuresis. Aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. We speculate that aripiprazole functioned as a D2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately.

Authors+Show Affiliations

Department of Psychiatry, Incheon Christian Hospital, Incheon, Korea.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20119596

Citation

Lee, Myung-Ji, and Chul-Eung Kim. "Use of Aripiprazole in Clozapine Induced Enuresis: Report of Two Cases." Journal of Korean Medical Science, vol. 25, no. 2, 2010, pp. 333-5.
Lee MJ, Kim CE. Use of aripiprazole in clozapine induced enuresis: report of two cases. J Korean Med Sci. 2010;25(2):333-5.
Lee, M. J., & Kim, C. E. (2010). Use of aripiprazole in clozapine induced enuresis: report of two cases. Journal of Korean Medical Science, 25(2), 333-5. https://doi.org/10.3346/jkms.2010.25.2.333
Lee MJ, Kim CE. Use of Aripiprazole in Clozapine Induced Enuresis: Report of Two Cases. J Korean Med Sci. 2010;25(2):333-5. PubMed PMID: 20119596.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of aripiprazole in clozapine induced enuresis: report of two cases. AU - Lee,Myung-Ji, AU - Kim,Chul-Eung, Y1 - 2010/01/19/ PY - 2008/03/25/received PY - 2008/09/19/accepted PY - 2010/2/2/entrez PY - 2010/2/2/pubmed PY - 2010/4/29/medline KW - Aripiprazole KW - Clozapine KW - Dopamine KW - Enuresis SP - 333 EP - 5 JF - Journal of Korean medical science JO - J. Korean Med. Sci. VL - 25 IS - 2 N2 - This report describes the efficacy of combined use of aripiprazole in the treatment of a patient with clozapine induced enuresis. Aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. We speculate that aripiprazole functioned as a D2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately. SN - 1598-6357 UR - https://www.unboundmedicine.com/medline/citation/20119596/Use_of_aripiprazole_in_clozapine_induced_enuresis:_report_of_two_cases_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2010.25.2.333 DB - PRIME DP - Unbound Medicine ER -