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Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia.
Nat Prod Commun. 2009 Dec; 4(12):1675-8.NP

Abstract

The essential oil from Anemia tomentosa var. anthriscifolia showed in vitro activity against Mycobacterium tuberculosis (MIC 100 microg/ml) and therefore was characterized by gas chromatography (GC) and by gas chromatography coupled with mass spectrometry (GC-MS). The major constituents of this essential oil were triquinane sesquiterpenes: silphiperfol-6-ene (14.7%), (-)-epi-presilphiperfolan-1-ol (30.6%), presilphiperfol-7-ene (3.9%), cameroonan-7 alpha-ol (4.4%), prenopsan-8-ol (1.9%) and presilphiperfolan-8-ol (8.3%), suggesting the existence of different chemotypes for this species. The essential oil was fractionated by column chromatography and its major constituent and fractions were assayed against Mycobacterium tuberculosis and M. smegmatis. (-)-epi-Presilphiperfolan-1-ol exhibited an MIC of 120 microg/ml against M. tuberculosis H37Rv.

Authors+Show Affiliations

Universidade Federal do Rio de Janeiro, Núcleo de Pesquisas de Produtos Naturais, CCS, Bloco H, Ilha do Fundão, 21941-590, Rio de Janeiro, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20120105

Citation

Pinto, Shaft Corrêa, et al. "Chemical Composition and Antimycobacterial Activity of the Essential Oil From Anemia Tomentosa Var. Anthriscifolia." Natural Product Communications, vol. 4, no. 12, 2009, pp. 1675-8.
Pinto SC, Leitão GG, de Oliveira DR, et al. Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia. Nat Prod Commun. 2009;4(12):1675-8.
Pinto, S. C., Leitão, G. G., de Oliveira, D. R., Bizzo, H. R., Ramos, D. F., Coelho, T. S., Silva, P. E., Lourenço, M. C., & Leitão, S. G. (2009). Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia. Natural Product Communications, 4(12), 1675-8.
Pinto SC, et al. Chemical Composition and Antimycobacterial Activity of the Essential Oil From Anemia Tomentosa Var. Anthriscifolia. Nat Prod Commun. 2009;4(12):1675-8. PubMed PMID: 20120105.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antimycobacterial activity of the essential oil from Anemia tomentosa var. anthriscifolia. AU - Pinto,Shaft Corrêa, AU - Leitão,Gilda Guimarães, AU - de Oliveira,Danilo Ribeiro, AU - Bizzo,Humberto Ribeiro, AU - Ramos,Daniela Fernandes, AU - Coelho,Tatiane Silveira, AU - Silva,Pedro Eduardo A, AU - Lourenço,Maria Cristina S, AU - Leitão,Suzana Guimarães, PY - 2010/2/3/entrez PY - 2010/2/3/pubmed PY - 2010/3/10/medline SP - 1675 EP - 8 JF - Natural product communications JO - Nat Prod Commun VL - 4 IS - 12 N2 - The essential oil from Anemia tomentosa var. anthriscifolia showed in vitro activity against Mycobacterium tuberculosis (MIC 100 microg/ml) and therefore was characterized by gas chromatography (GC) and by gas chromatography coupled with mass spectrometry (GC-MS). The major constituents of this essential oil were triquinane sesquiterpenes: silphiperfol-6-ene (14.7%), (-)-epi-presilphiperfolan-1-ol (30.6%), presilphiperfol-7-ene (3.9%), cameroonan-7 alpha-ol (4.4%), prenopsan-8-ol (1.9%) and presilphiperfolan-8-ol (8.3%), suggesting the existence of different chemotypes for this species. The essential oil was fractionated by column chromatography and its major constituent and fractions were assayed against Mycobacterium tuberculosis and M. smegmatis. (-)-epi-Presilphiperfolan-1-ol exhibited an MIC of 120 microg/ml against M. tuberculosis H37Rv. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20120105/Chemical_composition_and_antimycobacterial_activity_of_the_essential_oil_from_Anemia_tomentosa_var__anthriscifolia_ DB - PRIME DP - Unbound Medicine ER -