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Essential oils from two Lantana species with antimycobacterial activity.
Nat Prod Commun. 2009 Dec; 4(12):1733-6.NP

Abstract

Lantana trifolia L. and L. fucata Lindl. are two Brazilian species used in folk medicine for the treatment of respiratory disorders. The composition of the essential oils from the leaves was investigated, as well as their in vitro activity against Mycobacterium tuberculosis. L. trifolia yielded an oil (0.2%) rich in sesquiterpenes. The major substances found were germacrene D (45.1%), (E)-caryophyllene (12.8%), bicyclogermacrene (12.7%) and alpha-humulene (4.4%). Sesquiterpenes were also the main components of the oil of L. fucata (0.3% yield), the principal ones being beta-elemene (27.1%), germacrene D (11.6%), (E)-caryophyllene (7.7%), valencene (5.7%) and germacrene A (4.6%). Both oils exhibited in vitro antimycobacterial activity by the MABA assay with MICs of 80 microg/mL for L. trifolia and 100 microg/mL for L. fucata.

Authors+Show Affiliations

Programa de Biotecnologia Vegetal, Universidade Federal do Rio de Janeiro, CCS, Bl. K. 2 andar, Rio de Janeiro, RJ, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20120116

Citation

Julião, Lisieux de Santana, et al. "Essential Oils From Two Lantana Species With Antimycobacterial Activity." Natural Product Communications, vol. 4, no. 12, 2009, pp. 1733-6.
Julião Lde S, Bizzo HR, Souza AM, et al. Essential oils from two Lantana species with antimycobacterial activity. Nat Prod Commun. 2009;4(12):1733-6.
Julião, L. d. e. . S., Bizzo, H. R., Souza, A. M., Lourenço, M. C., Silva, P. E., Tavares, E. S., Rastrelli, L., & Leitão, S. G. (2009). Essential oils from two Lantana species with antimycobacterial activity. Natural Product Communications, 4(12), 1733-6.
Julião Lde S, et al. Essential Oils From Two Lantana Species With Antimycobacterial Activity. Nat Prod Commun. 2009;4(12):1733-6. PubMed PMID: 20120116.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Essential oils from two Lantana species with antimycobacterial activity. AU - Julião,Lisieux de Santana, AU - Bizzo,Humberto R, AU - Souza,Andressa M, AU - Lourenço,Maria Cristina S, AU - Silva,Pedro Eduardo A, AU - Tavares,Eliana S, AU - Rastrelli,Luca, AU - Leitão,Suzana Guimarães, PY - 2010/2/3/entrez PY - 2010/2/3/pubmed PY - 2010/3/10/medline SP - 1733 EP - 6 JF - Natural product communications JO - Nat Prod Commun VL - 4 IS - 12 N2 - Lantana trifolia L. and L. fucata Lindl. are two Brazilian species used in folk medicine for the treatment of respiratory disorders. The composition of the essential oils from the leaves was investigated, as well as their in vitro activity against Mycobacterium tuberculosis. L. trifolia yielded an oil (0.2%) rich in sesquiterpenes. The major substances found were germacrene D (45.1%), (E)-caryophyllene (12.8%), bicyclogermacrene (12.7%) and alpha-humulene (4.4%). Sesquiterpenes were also the main components of the oil of L. fucata (0.3% yield), the principal ones being beta-elemene (27.1%), germacrene D (11.6%), (E)-caryophyllene (7.7%), valencene (5.7%) and germacrene A (4.6%). Both oils exhibited in vitro antimycobacterial activity by the MABA assay with MICs of 80 microg/mL for L. trifolia and 100 microg/mL for L. fucata. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20120116/Essential_oils_from_two_Lantana_species_with_antimycobacterial_activity_ DB - PRIME DP - Unbound Medicine ER -