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The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders.
J Drugs Dermatol. 2010 Jan; 9(1):41-8.JD

Abstract

Scalp lesions are common among patients with psoriasis, seborrheic dermatitis and a number of other inflammatory and fungal conditions. Topical corticosteroids are a mainstay of treatment for many scalp dermatoses and they significantly reduce erythema, scaling and pruritus. Conventional corticosteroid formulations such as cream and ointments are often difficult or time consuming for patients to apply and may produce undesirable cosmetic effects. Medicated shampoos provide a more convenient alternative for patients who require topical administration of corticosteroids for scalp conditions. Tar shampoos have long been used to treat psoriasis and are effective for the long-term maintenance of remission in patients who respond to therapy. Antifungal shampoos are effective for the treatment of seborrheic dermatitis and other mycotic conditions. A shampoo formulation containing fluocinolone acetonide, 0.01% is also approved for the treatment of seborrheic dermatitis. One superpotent corticosteroid shampoo (clobetasol propionate 0.05%; Clobex Shampoo) is approved in the United States (U.S.) for once-daily treatment of psoriasis of the scalp. The results of a 2007 pilot study also demonstrated that clobetasol propionate shampoo improved the signs and symptoms of seborrheic dermatitis. These findings suggest that high-potency corticosteroid shampoos may provide an important option for topical corticosteroid therapy in dermatologic conditions affecting the scalp.

Authors+Show Affiliations

Physicians Skin Care, Louisville, KY 40217, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

20120424

Citation

Kircik, Leon. "The Evolving Role of Therapeutic Shampoos for Targeting Symptoms of Inflammatory Scalp Disorders." Journal of Drugs in Dermatology : JDD, vol. 9, no. 1, 2010, pp. 41-8.
Kircik L. The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders. J Drugs Dermatol. 2010;9(1):41-8.
Kircik, L. (2010). The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders. Journal of Drugs in Dermatology : JDD, 9(1), 41-8.
Kircik L. The Evolving Role of Therapeutic Shampoos for Targeting Symptoms of Inflammatory Scalp Disorders. J Drugs Dermatol. 2010;9(1):41-8. PubMed PMID: 20120424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders. A1 - Kircik,Leon, PY - 2010/2/3/entrez PY - 2010/2/3/pubmed PY - 2010/3/3/medline SP - 41 EP - 8 JF - Journal of drugs in dermatology : JDD JO - J Drugs Dermatol VL - 9 IS - 1 N2 - Scalp lesions are common among patients with psoriasis, seborrheic dermatitis and a number of other inflammatory and fungal conditions. Topical corticosteroids are a mainstay of treatment for many scalp dermatoses and they significantly reduce erythema, scaling and pruritus. Conventional corticosteroid formulations such as cream and ointments are often difficult or time consuming for patients to apply and may produce undesirable cosmetic effects. Medicated shampoos provide a more convenient alternative for patients who require topical administration of corticosteroids for scalp conditions. Tar shampoos have long been used to treat psoriasis and are effective for the long-term maintenance of remission in patients who respond to therapy. Antifungal shampoos are effective for the treatment of seborrheic dermatitis and other mycotic conditions. A shampoo formulation containing fluocinolone acetonide, 0.01% is also approved for the treatment of seborrheic dermatitis. One superpotent corticosteroid shampoo (clobetasol propionate 0.05%; Clobex Shampoo) is approved in the United States (U.S.) for once-daily treatment of psoriasis of the scalp. The results of a 2007 pilot study also demonstrated that clobetasol propionate shampoo improved the signs and symptoms of seborrheic dermatitis. These findings suggest that high-potency corticosteroid shampoos may provide an important option for topical corticosteroid therapy in dermatologic conditions affecting the scalp. SN - 1545-9616 UR - https://www.unboundmedicine.com/medline/citation/20120424/The_evolving_role_of_therapeutic_shampoos_for_targeting_symptoms_of_inflammatory_scalp_disorders_ L2 - https://medlineplus.gov/steroids.html DB - PRIME DP - Unbound Medicine ER -
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