Tags

Type your tag names separated by a space and hit enter

Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy.
J Obstet Gynaecol. 2010 Jan; 30(1):38-40.JO

Abstract

This retrospective cohort study was conducted at Newham University Hospital, London to investigate maternal outcome of planned vaginal delivery as well as rate of maternal-to-child transmission. Between June 2004 and June 2006, 23 (16%) women of 144 HIV-infected pregnant women opted for planned vaginal delivery. Offer of vaginal delivery was based on maternal HIV RNA count <50 cells/ml around 36 weeks' gestation. All women received antiretroviral therapy. Fifteen (65%) women achieved vaginal delivery. Babies were followed up over 18 months. All babies had antiretroviral prophylaxis. No babies were breast-fed. There was no report of maternal-to-child transmission in any of these babies. Our study suggests that planned vaginal delivery could be safe with antiretroviral therapy in pregnancy, optimal intrapartum care, viral load of <1000 copies/ml at delivery, retroviral prophylaxis for babies and avoidance of breast-feeding.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Islam S
Department of Obstetrics and Gynaecology, Newham University Hospital, London, UK. shahedaislam@yahoo.co.uk
Oon V
No affiliation info available
Thomas P
No affiliation info available

MeSH

AdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCohort StudiesDelivery, ObstetricFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPregnancy OutcomeRetrospective StudiesTerm BirthViral LoadYoung Adult

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20121502

Citation

Islam, S, et al. "Outcome of Pregnancy in HIV-positive Women Planned for Vaginal Delivery Under Effective Antiretroviral Therapy." Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, vol. 30, no. 1, 2010, pp. 38-40.
Islam S, Oon V, Thomas P. Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. J Obstet Gynaecol. 2010;30(1):38-40.
Islam, S., Oon, V., & Thomas, P. (2010). Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 30(1), 38-40. https://doi.org/10.3109/01443610903383358
Islam S, Oon V, Thomas P. Outcome of Pregnancy in HIV-positive Women Planned for Vaginal Delivery Under Effective Antiretroviral Therapy. J Obstet Gynaecol. 2010;30(1):38-40. PubMed PMID: 20121502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. AU - Islam,S, AU - Oon,V, AU - Thomas,P, PY - 2010/2/4/entrez PY - 2010/2/4/pubmed PY - 2010/5/1/medline SP - 38 EP - 40 JF - Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology JO - J Obstet Gynaecol VL - 30 IS - 1 N2 - This retrospective cohort study was conducted at Newham University Hospital, London to investigate maternal outcome of planned vaginal delivery as well as rate of maternal-to-child transmission. Between June 2004 and June 2006, 23 (16%) women of 144 HIV-infected pregnant women opted for planned vaginal delivery. Offer of vaginal delivery was based on maternal HIV RNA count <50 cells/ml around 36 weeks' gestation. All women received antiretroviral therapy. Fifteen (65%) women achieved vaginal delivery. Babies were followed up over 18 months. All babies had antiretroviral prophylaxis. No babies were breast-fed. There was no report of maternal-to-child transmission in any of these babies. Our study suggests that planned vaginal delivery could be safe with antiretroviral therapy in pregnancy, optimal intrapartum care, viral load of <1000 copies/ml at delivery, retroviral prophylaxis for babies and avoidance of breast-feeding. SN - 1364-6893 UR - https://www.unboundmedicine.com/medline/citation/20121502/Outcome_of_pregnancy_in_HIV_positive_women_planned_for_vaginal_delivery_under_effective_antiretroviral_therapy_ DB - PRIME DP - Unbound Medicine ER -