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Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy.
J Obstet Gynaecol. 2010 Jan; 30(1):38-40.JO

Abstract

This retrospective cohort study was conducted at Newham University Hospital, London to investigate maternal outcome of planned vaginal delivery as well as rate of maternal-to-child transmission. Between June 2004 and June 2006, 23 (16%) women of 144 HIV-infected pregnant women opted for planned vaginal delivery. Offer of vaginal delivery was based on maternal HIV RNA count <50 cells/ml around 36 weeks' gestation. All women received antiretroviral therapy. Fifteen (65%) women achieved vaginal delivery. Babies were followed up over 18 months. All babies had antiretroviral prophylaxis. No babies were breast-fed. There was no report of maternal-to-child transmission in any of these babies. Our study suggests that planned vaginal delivery could be safe with antiretroviral therapy in pregnancy, optimal intrapartum care, viral load of <1000 copies/ml at delivery, retroviral prophylaxis for babies and avoidance of breast-feeding.

Authors+Show Affiliations

Department of Obstetrics and Gynaecology, Newham University Hospital, London, UK. shahedaislam@yahoo.co.ukNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20121502

Citation

Islam, S, et al. "Outcome of Pregnancy in HIV-positive Women Planned for Vaginal Delivery Under Effective Antiretroviral Therapy." Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, vol. 30, no. 1, 2010, pp. 38-40.
Islam S, Oon V, Thomas P. Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. J Obstet Gynaecol. 2010;30(1):38-40.
Islam, S., Oon, V., & Thomas, P. (2010). Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 30(1), 38-40. https://doi.org/10.3109/01443610903383358
Islam S, Oon V, Thomas P. Outcome of Pregnancy in HIV-positive Women Planned for Vaginal Delivery Under Effective Antiretroviral Therapy. J Obstet Gynaecol. 2010;30(1):38-40. PubMed PMID: 20121502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of pregnancy in HIV-positive women planned for vaginal delivery under effective antiretroviral therapy. AU - Islam,S, AU - Oon,V, AU - Thomas,P, PY - 2010/2/4/entrez PY - 2010/2/4/pubmed PY - 2010/5/1/medline SP - 38 EP - 40 JF - Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology JO - J Obstet Gynaecol VL - 30 IS - 1 N2 - This retrospective cohort study was conducted at Newham University Hospital, London to investigate maternal outcome of planned vaginal delivery as well as rate of maternal-to-child transmission. Between June 2004 and June 2006, 23 (16%) women of 144 HIV-infected pregnant women opted for planned vaginal delivery. Offer of vaginal delivery was based on maternal HIV RNA count <50 cells/ml around 36 weeks' gestation. All women received antiretroviral therapy. Fifteen (65%) women achieved vaginal delivery. Babies were followed up over 18 months. All babies had antiretroviral prophylaxis. No babies were breast-fed. There was no report of maternal-to-child transmission in any of these babies. Our study suggests that planned vaginal delivery could be safe with antiretroviral therapy in pregnancy, optimal intrapartum care, viral load of <1000 copies/ml at delivery, retroviral prophylaxis for babies and avoidance of breast-feeding. SN - 1364-6893 UR - https://www.unboundmedicine.com/medline/citation/20121502/Outcome_of_pregnancy_in_HIV_positive_women_planned_for_vaginal_delivery_under_effective_antiretroviral_therapy_ DB - PRIME DP - Unbound Medicine ER -