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Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality.
Acta Radiol. 2010 Apr; 51(3):260-70.AR

Abstract

BACKGROUND

Concern has been raised regarding the mounting collective radiation doses from computed tomography (CT), increasing the risk of radiation-induced cancers in exposed populations.

PURPOSE

To compare radiation dose and image quality in a chest phantom and in patients for the diagnosis of pulmonary embolism (PE) at 100 and 120 peak kilovoltage (kVp) using 16-multichannel detector computed tomography (MDCT).

MATERIAL AND METHODS

A 20-ml syringe containing 12 mg I/ml was scanned in a chest phantom at 100/120 kVp and 25 milliampere seconds (mAs). Consecutive patients underwent 100 kVp (n = 50) and 120 kVp (n = 50) 16-MDCT using a "quality reference" effective mAs of 100, 300 mg I/kg, and a 12-s injection duration. Attenuation (CT number), image noise (1 standard deviation), and contrast-to-noise ratio (CNR; fresh clot = 70 HU) of the contrast medium syringe and pulmonary arteries were evaluated on 3-mm-thick slices. Subjective image quality was assessed. Computed tomography dose index (CTDI(vol)) and dose-length product (DLP) were presented by the CT software, and effective dose was estimated.

RESULTS

Mean values in the chest phantom and patients changed as follows when X-ray tube potential decreased from 120 to 100 kVp: attenuation +23% and +40%, noise +38% and +48%, CNR -6% and 0%, and CTDI(vol) -38% and -40%, respectively. Mean DLP and effective dose in the patients decreased by 42% and 45%, respectively. Subjective image quality was excellent or adequate in 49/48 patients at 100/120 kVp. No patient with a negative CT had any thromboembolism diagnosed during 3-month follow-up.

CONCLUSION

By reducing X-ray tube potential from 120 to 100 kVp, while keeping all other scanning parameters unchanged, the radiation dose to the patient may be almost halved without deterioration of diagnostic quality, which may be of particular benefit in young individuals.

Authors+Show Affiliations

Department of Radiology, University of Lund, Lasarettet Trelleborg, Trelleborg, Sweden.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20121673

Citation

Björkdahl, Peter, and Ulf Nyman. "Using 100- Instead of 120-kVp Computed Tomography to Diagnose Pulmonary Embolism Almost Halves the Radiation Dose With Preserved Diagnostic Quality." Acta Radiologica (Stockholm, Sweden : 1987), vol. 51, no. 3, 2010, pp. 260-70.
Björkdahl P, Nyman U. Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality. Acta Radiol. 2010;51(3):260-70.
Björkdahl, P., & Nyman, U. (2010). Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality. Acta Radiologica (Stockholm, Sweden : 1987), 51(3), 260-70. https://doi.org/10.3109/02841850903505222
Björkdahl P, Nyman U. Using 100- Instead of 120-kVp Computed Tomography to Diagnose Pulmonary Embolism Almost Halves the Radiation Dose With Preserved Diagnostic Quality. Acta Radiol. 2010;51(3):260-70. PubMed PMID: 20121673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality. AU - Björkdahl,Peter, AU - Nyman,Ulf, PY - 2010/2/4/entrez PY - 2010/2/4/pubmed PY - 2010/4/3/medline SP - 260 EP - 70 JF - Acta radiologica (Stockholm, Sweden : 1987) JO - Acta Radiol VL - 51 IS - 3 N2 - BACKGROUND: Concern has been raised regarding the mounting collective radiation doses from computed tomography (CT), increasing the risk of radiation-induced cancers in exposed populations. PURPOSE: To compare radiation dose and image quality in a chest phantom and in patients for the diagnosis of pulmonary embolism (PE) at 100 and 120 peak kilovoltage (kVp) using 16-multichannel detector computed tomography (MDCT). MATERIAL AND METHODS: A 20-ml syringe containing 12 mg I/ml was scanned in a chest phantom at 100/120 kVp and 25 milliampere seconds (mAs). Consecutive patients underwent 100 kVp (n = 50) and 120 kVp (n = 50) 16-MDCT using a "quality reference" effective mAs of 100, 300 mg I/kg, and a 12-s injection duration. Attenuation (CT number), image noise (1 standard deviation), and contrast-to-noise ratio (CNR; fresh clot = 70 HU) of the contrast medium syringe and pulmonary arteries were evaluated on 3-mm-thick slices. Subjective image quality was assessed. Computed tomography dose index (CTDI(vol)) and dose-length product (DLP) were presented by the CT software, and effective dose was estimated. RESULTS: Mean values in the chest phantom and patients changed as follows when X-ray tube potential decreased from 120 to 100 kVp: attenuation +23% and +40%, noise +38% and +48%, CNR -6% and 0%, and CTDI(vol) -38% and -40%, respectively. Mean DLP and effective dose in the patients decreased by 42% and 45%, respectively. Subjective image quality was excellent or adequate in 49/48 patients at 100/120 kVp. No patient with a negative CT had any thromboembolism diagnosed during 3-month follow-up. CONCLUSION: By reducing X-ray tube potential from 120 to 100 kVp, while keeping all other scanning parameters unchanged, the radiation dose to the patient may be almost halved without deterioration of diagnostic quality, which may be of particular benefit in young individuals. SN - 1600-0455 UR - https://www.unboundmedicine.com/medline/citation/20121673/Using_100__instead_of_120_kVp_computed_tomography_to_diagnose_pulmonary_embolism_almost_halves_the_radiation_dose_with_preserved_diagnostic_quality_ L2 - https://journals.sagepub.com/doi/10.3109/02841850903505222?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -