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Earlier versus later continuous Kangaroo Mother Care (KMC) for stable low-birth-weight infants: a randomized controlled trial.
Acta Paediatr. 2010 Jun; 99(6):827-35.AP

Abstract

AIM

The aim of this study was to examine the effectiveness of earlier continuous Kangaroo Mother Care (KMC) for relatively stable low-birth-weight (LBW) infants in a resource-limited country.

METHODS

A randomized controlled trial was performed in LBW infants at a referral hospital in Madagascar. Earlier continuous KMC (intervention) was begun as soon as possible, within 24 h postbirth, and later continuous KMC (control: conventional care) was begun after complete stabilization (generally after 24 h postbirth). Main outcome measure was mortality during the first 28 days postbirth. This trial was registered with ClinicalTrials.gov, NCT00531492.

RESULTS

A total of 73 infants (intervention 37, control 36) were included. Earlier continuous KMC had higher but no statistically different mortality in the first 28 days postbirth (1 vs. 2; risk ratio, 1.95; 95% CIs, 0.18-20.53; p = 1.00). There were no differences in incidence of morbidities. Body weight loss from birth to 24 h postbirth was significantly less in earlier KMC infants compared with later KMC infants. (-34.81 g vs. -73.97 g; mean difference, 39.16 g; 95% CIs, 10.30-68.03; p = 0.01; adjusted p = 0.02). Adverse events and duration of hospitalization were not different between the two groups.

CONCLUSION

Further evaluations of earlier continuous KMC including measurement of KMC dose, are needed in resource-limited countries.

Authors+Show Affiliations

Department of Health Informatics, School of Public Health, Kyoto University, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20121708

Citation

Nagai, S, et al. "Earlier Versus Later Continuous Kangaroo Mother Care (KMC) for Stable Low-birth-weight Infants: a Randomized Controlled Trial." Acta Paediatrica (Oslo, Norway : 1992), vol. 99, no. 6, 2010, pp. 827-35.
Nagai S, Andrianarimanana D, Rabesandratana N, et al. Earlier versus later continuous Kangaroo Mother Care (KMC) for stable low-birth-weight infants: a randomized controlled trial. Acta Paediatr. 2010;99(6):827-35.
Nagai, S., Andrianarimanana, D., Rabesandratana, N., Yonemoto, N., Nakayama, T., & Mori, R. (2010). Earlier versus later continuous Kangaroo Mother Care (KMC) for stable low-birth-weight infants: a randomized controlled trial. Acta Paediatrica (Oslo, Norway : 1992), 99(6), 827-35. https://doi.org/10.1111/j.1651-2227.2009.01676.x
Nagai S, et al. Earlier Versus Later Continuous Kangaroo Mother Care (KMC) for Stable Low-birth-weight Infants: a Randomized Controlled Trial. Acta Paediatr. 2010;99(6):827-35. PubMed PMID: 20121708.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Earlier versus later continuous Kangaroo Mother Care (KMC) for stable low-birth-weight infants: a randomized controlled trial. AU - Nagai,S, AU - Andrianarimanana,D, AU - Rabesandratana,N, AU - Yonemoto,N, AU - Nakayama,T, AU - Mori,R, Y1 - 2010/01/27/ PY - 2010/2/4/entrez PY - 2010/2/4/pubmed PY - 2010/8/18/medline SP - 827 EP - 35 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr VL - 99 IS - 6 N2 - AIM: The aim of this study was to examine the effectiveness of earlier continuous Kangaroo Mother Care (KMC) for relatively stable low-birth-weight (LBW) infants in a resource-limited country. METHODS: A randomized controlled trial was performed in LBW infants at a referral hospital in Madagascar. Earlier continuous KMC (intervention) was begun as soon as possible, within 24 h postbirth, and later continuous KMC (control: conventional care) was begun after complete stabilization (generally after 24 h postbirth). Main outcome measure was mortality during the first 28 days postbirth. This trial was registered with ClinicalTrials.gov, NCT00531492. RESULTS: A total of 73 infants (intervention 37, control 36) were included. Earlier continuous KMC had higher but no statistically different mortality in the first 28 days postbirth (1 vs. 2; risk ratio, 1.95; 95% CIs, 0.18-20.53; p = 1.00). There were no differences in incidence of morbidities. Body weight loss from birth to 24 h postbirth was significantly less in earlier KMC infants compared with later KMC infants. (-34.81 g vs. -73.97 g; mean difference, 39.16 g; 95% CIs, 10.30-68.03; p = 0.01; adjusted p = 0.02). Adverse events and duration of hospitalization were not different between the two groups. CONCLUSION: Further evaluations of earlier continuous KMC including measurement of KMC dose, are needed in resource-limited countries. SN - 1651-2227 UR - https://www.unboundmedicine.com/medline/citation/20121708/Earlier_versus_later_continuous_Kangaroo_Mother_Care__KMC__for_stable_low_birth_weight_infants:_a_randomized_controlled_trial_ L2 - https://doi.org/10.1111/j.1651-2227.2009.01676.x DB - PRIME DP - Unbound Medicine ER -