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Antimuscarinics and bladder outlet obstruction: From a contraindication to an indication?
Neurourol Urodyn. 2010; 29 Suppl 1:S46-50.NU

Abstract

AIM

To review if the existing data support the new concept that antimuscarinic agents can be used for the treatment of bladder outlet obstruction (BOO) with coexisting overactive bladder (OAB).

METHOD

A literature search of Medline publications (up to 2008) on use of antimuscarinic agents for treatment BOO was performed and all data were presented. All relevant data from published studies in congress abstracts were as well included.

RESULTS

The existing data show that this treatment effectively improves patient quality of life. Concerns about the possibility of urinary retention were shown to be unfounded. It seems that antimuscarinic agents do not affect voiding pressures and the use of antimuscarinic agents for BOO seems safe.

CONCLUSIONS

The combination of an alpha-blocker and antimuscarinic agent for the treatment of BOO with concomitant OAB seems promising.

Authors+Show Affiliations

Urodynamic Urology Unit, Department of Urology, Medical School, University of Patras, Patras, Greece. tassos_athan@hotmail.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20127792

Citation

Athanasopoulos, Anastasios. "Antimuscarinics and Bladder Outlet Obstruction: From a Contraindication to an Indication?" Neurourology and Urodynamics, vol. 29 Suppl 1, 2010, pp. S46-50.
Athanasopoulos A. Antimuscarinics and bladder outlet obstruction: From a contraindication to an indication? Neurourol Urodyn. 2010;29 Suppl 1:S46-50.
Athanasopoulos, A. (2010). Antimuscarinics and bladder outlet obstruction: From a contraindication to an indication? Neurourology and Urodynamics, 29 Suppl 1, S46-50. https://doi.org/10.1002/nau.20807
Athanasopoulos A. Antimuscarinics and Bladder Outlet Obstruction: From a Contraindication to an Indication. Neurourol Urodyn. 2010;29 Suppl 1:S46-50. PubMed PMID: 20127792.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimuscarinics and bladder outlet obstruction: From a contraindication to an indication? A1 - Athanasopoulos,Anastasios, PY - 2010/2/4/entrez PY - 2010/2/4/pubmed PY - 2010/8/26/medline SP - S46 EP - 50 JF - Neurourology and urodynamics JO - Neurourol Urodyn VL - 29 Suppl 1 N2 - AIM: To review if the existing data support the new concept that antimuscarinic agents can be used for the treatment of bladder outlet obstruction (BOO) with coexisting overactive bladder (OAB). METHOD: A literature search of Medline publications (up to 2008) on use of antimuscarinic agents for treatment BOO was performed and all data were presented. All relevant data from published studies in congress abstracts were as well included. RESULTS: The existing data show that this treatment effectively improves patient quality of life. Concerns about the possibility of urinary retention were shown to be unfounded. It seems that antimuscarinic agents do not affect voiding pressures and the use of antimuscarinic agents for BOO seems safe. CONCLUSIONS: The combination of an alpha-blocker and antimuscarinic agent for the treatment of BOO with concomitant OAB seems promising. SN - 1520-6777 UR - https://www.unboundmedicine.com/medline/citation/20127792/Antimuscarinics_and_bladder_outlet_obstruction:_From_a_contraindication_to_an_indication L2 - https://doi.org/10.1002/nau.20807 DB - PRIME DP - Unbound Medicine ER -