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Nasal vestibular huge keratoacanthoma: an unusual site.
Pak J Biol Sci. 2009 Oct 15; 12(20):1385-7.PJ

Abstract

Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence. This tumor is dome-shaped nodule with a central keratinous plug. The etiology of this tumor is not obvious. Exposure to excessive sunlight is the most frequently noted responsible factor in the etiology of KA. About 80% of the tumors occur on the face. The histological features of the KA are often very similar to those of a cutaneous squamous cell carcinoma; however, the tumor structure usually provides a basis for their difference. There are many unusual cases of keratoacanthoma reported regarding site, size or other specifications. In this study, we excised a mass of nasal vestibule, a site far away sun-exposure. To our knowledge, this is the first case of nasal vestibular keratoacanthoma. For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management.

Authors+Show Affiliations

Otorhinolaryngology Research Centre, Department of Otolaryngology, Head and Neck Surgery, Tehran University of Medical Sciences, Amir-A'lam Hospital, Tehran, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20128508

Citation

Yazdani, N, et al. "Nasal Vestibular Huge Keratoacanthoma: an Unusual Site." Pakistan Journal of Biological Sciences : PJBS, vol. 12, no. 20, 2009, pp. 1385-7.
Yazdani N, Khorsandi-Ashtiani M, Rabbani-Anari M, et al. Nasal vestibular huge keratoacanthoma: an unusual site. Pak J Biol Sci. 2009;12(20):1385-7.
Yazdani, N., Khorsandi-Ashtiani, M., Rabbani-Anari, M., Bassam, A., & Kouhi, A. (2009). Nasal vestibular huge keratoacanthoma: an unusual site. Pakistan Journal of Biological Sciences : PJBS, 12(20), 1385-7.
Yazdani N, et al. Nasal Vestibular Huge Keratoacanthoma: an Unusual Site. Pak J Biol Sci. 2009 Oct 15;12(20):1385-7. PubMed PMID: 20128508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nasal vestibular huge keratoacanthoma: an unusual site. AU - Yazdani,N, AU - Khorsandi-Ashtiani,M, AU - Rabbani-Anari,M, AU - Bassam,A, AU - Kouhi,A, PY - 2010/2/5/entrez PY - 2010/2/5/pubmed PY - 2010/4/28/medline SP - 1385 EP - 7 JF - Pakistan journal of biological sciences : PJBS JO - Pak J Biol Sci VL - 12 IS - 20 N2 - Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence. This tumor is dome-shaped nodule with a central keratinous plug. The etiology of this tumor is not obvious. Exposure to excessive sunlight is the most frequently noted responsible factor in the etiology of KA. About 80% of the tumors occur on the face. The histological features of the KA are often very similar to those of a cutaneous squamous cell carcinoma; however, the tumor structure usually provides a basis for their difference. There are many unusual cases of keratoacanthoma reported regarding site, size or other specifications. In this study, we excised a mass of nasal vestibule, a site far away sun-exposure. To our knowledge, this is the first case of nasal vestibular keratoacanthoma. For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management. SN - 1028-8880 UR - https://www.unboundmedicine.com/medline/citation/20128508/Nasal_vestibular_huge_keratoacanthoma:_an_unusual_site_ DB - PRIME DP - Unbound Medicine ER -