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Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery - 12-month follow-up.
Kardiol Pol. 2010 Jan; 68(1):22-30.KP

Abstract

BACKGROUND

Treatment of chronic diseases, such as atherosclerosis, usually leads to significant short-term improvement. Mid- and long-term results are not always as satisfactory. That is why improvement of quality of life should be the leading qualification criterion for invasive procedures, which sometimes carry a risk of complications.

AIM

To determine the quality of life in patients with stable, multivessel coronary artery disease (MCAD), treated surgically or medically.

METHODS

The study group comprised 107 patients (pts; 80 males) suffering from MCAD, assigned to coronary artery bypass grafting (CABG) (55 pts) or to medical treatment alone (52 pts). The mean Gensini score in the whole group was 90 (66-132). To evaluate quality of life we used a Short Form-36 (SF-36) health status survey by the International Quality of Life Assessment Project.

RESULTS

During a 12-month follow-up 9 pts died (6 pts in the medically treated group and 3 in the CABG group), all for cardiovascular reasons. Patients treated conservatively were more often hospitalised due to angina symptoms (20 vs. 5, p = 0.003). Analysis of SF-36 showed that pts treated surgically had better improvement of quality of life in comparison with medically treated patients. Significant differences were found for physical functioning, bodily pain, vitality, mental health and mental component summary.

CONCLUSIONS

This study has shown that there is a significant difference in health-related quality of life 12 months after CABG surgery and medical treatment alone in high-risk patients with MCAD. Surgical treatment decreases the number of adverse events, better attenuates of anginal and heart failure symptoms, and improves the quality of life, especially the mental component. Our results should encouraged selecting patients with advanced atherosclerosis for revascularisation procedures, even if there is a very high peri-procedural risk.

Authors+Show Affiliations

2nd Department of Cardiology, Medical University, Lodz, Poland. rkrecki@gazeta.plNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20131185

Citation

Krecki, Radosław, et al. "Quality of Life in High-risk Patients With Stable Multivessel Coronary Artery Disease Treated Either Medically or With Coronary Artery Bypass Graft Surgery - 12-month Follow-up." Kardiologia Polska, vol. 68, no. 1, 2010, pp. 22-30.
Krecki R, Drozdz J, Szcześniak P, et al. Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery - 12-month follow-up. Kardiol Pol. 2010;68(1):22-30.
Krecki, R., Drozdz, J., Szcześniak, P., Kasprzak, J. D., Peruga, J. Z., Lipiec, P., Wierzbowska-Drabik, K., Foryś, J., Orszulak-Michalak, D., & Krzemińska-Pakuła, M. (2010). Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery - 12-month follow-up. Kardiologia Polska, 68(1), 22-30.
Krecki R, et al. Quality of Life in High-risk Patients With Stable Multivessel Coronary Artery Disease Treated Either Medically or With Coronary Artery Bypass Graft Surgery - 12-month Follow-up. Kardiol Pol. 2010;68(1):22-30. PubMed PMID: 20131185.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quality of life in high-risk patients with stable multivessel coronary artery disease treated either medically or with coronary artery bypass graft surgery - 12-month follow-up. AU - Krecki,Radosław, AU - Drozdz,Jarosław, AU - Szcześniak,Piotr, AU - Kasprzak,Jarosław D, AU - Peruga,Jan Z, AU - Lipiec,Piotr, AU - Wierzbowska-Drabik,Karina, AU - Foryś,Jakub, AU - Orszulak-Michalak,Daria, AU - Krzemińska-Pakuła,Maria, PY - 2010/2/5/entrez PY - 2010/2/5/pubmed PY - 2010/4/17/medline SP - 22 EP - 30 JF - Kardiologia polska JO - Kardiol Pol VL - 68 IS - 1 N2 - BACKGROUND: Treatment of chronic diseases, such as atherosclerosis, usually leads to significant short-term improvement. Mid- and long-term results are not always as satisfactory. That is why improvement of quality of life should be the leading qualification criterion for invasive procedures, which sometimes carry a risk of complications. AIM: To determine the quality of life in patients with stable, multivessel coronary artery disease (MCAD), treated surgically or medically. METHODS: The study group comprised 107 patients (pts; 80 males) suffering from MCAD, assigned to coronary artery bypass grafting (CABG) (55 pts) or to medical treatment alone (52 pts). The mean Gensini score in the whole group was 90 (66-132). To evaluate quality of life we used a Short Form-36 (SF-36) health status survey by the International Quality of Life Assessment Project. RESULTS: During a 12-month follow-up 9 pts died (6 pts in the medically treated group and 3 in the CABG group), all for cardiovascular reasons. Patients treated conservatively were more often hospitalised due to angina symptoms (20 vs. 5, p = 0.003). Analysis of SF-36 showed that pts treated surgically had better improvement of quality of life in comparison with medically treated patients. Significant differences were found for physical functioning, bodily pain, vitality, mental health and mental component summary. CONCLUSIONS: This study has shown that there is a significant difference in health-related quality of life 12 months after CABG surgery and medical treatment alone in high-risk patients with MCAD. Surgical treatment decreases the number of adverse events, better attenuates of anginal and heart failure symptoms, and improves the quality of life, especially the mental component. Our results should encouraged selecting patients with advanced atherosclerosis for revascularisation procedures, even if there is a very high peri-procedural risk. SN - 0022-9032 UR - https://www.unboundmedicine.com/medline/citation/20131185/Quality_of_life_in_high_risk_patients_with_stable_multivessel_coronary_artery_disease_treated_either_medically_or_with_coronary_artery_bypass_graft_surgery___12_month_follow_up_ L2 - https://medlineplus.gov/coronaryarterydisease.html DB - PRIME DP - Unbound Medicine ER -