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Influence of diabetes on the outcome of acute coronary syndrome in Kuwait.
Med Princ Pract. 2010; 19(2):113-7.MP

Abstract

OBJECTIVES

To describe the baseline characteristics and management of patients with and without diabetes mellitus (DM) hospitalized with acute myocardial infarction (AMI) and to assess the influence of DM on hospital outcomes and hospital mortality.

SUBJECTS AND METHODS

We analyzed data from a 6-month observational study (Kuwait Acute Coronary Syndrome Registry) of unselected patients admitted with a diagnosis of AMI over a period of 6 months, from December 2003 through May 2004.

RESULTS

Of 1,295 patients enrolled, 609 (47%) were diabetics and 686 (53%) were non-diabetics. Diabetics were more likely to have a past history of coronary artery disease, hypertension and left ventricular systolic dysfunction than non-diabetics. There was less use of beta-blockers and aspirin in diabetics as compared to non-diabetics (62 vs. 71% and 95.5 vs. 97.9%, p < 0.03, for beta-blockers and aspirin, respectively). Left ventricular failure and cardiogenic shock occurred more often in diabetics compared to non-diabetics (16 vs. 7% and 5 vs. 3%, p < 0.001, for left ventricular failure and shock, respectively). The mortality rate was 6% for diabetics and 2% for non-diabetics (p < 0.001).

CONCLUSION

DM is a major health problem among the adult population in Kuwait, and almost half the AMI population suffer from diabetes. Diabetic patients had higher rates of complications, especially left ventricular failure and cardiogenic shock, as compared to non-diabetic patients. The in-hospital mortality among diabetics with AMI was almost triple that of non-diabetics. The results of this study highlight the need to improve adherence to evidence-based treatment in diabetic patients with AMI.

Authors+Show Affiliations

Department of Medicine, Mubarak Al-Kabeer Hospital, Kuwait.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20134173

Citation

Saad, Hisham, et al. "Influence of Diabetes On the Outcome of Acute Coronary Syndrome in Kuwait." Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, vol. 19, no. 2, 2010, pp. 113-7.
Saad H, Sawan S, Rashed W, et al. Influence of diabetes on the outcome of acute coronary syndrome in Kuwait. Med Princ Pract. 2010;19(2):113-7.
Saad, H., Sawan, S., Rashed, W., & Zubaid, M. (2010). Influence of diabetes on the outcome of acute coronary syndrome in Kuwait. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, 19(2), 113-7. https://doi.org/10.1159/000273070
Saad H, et al. Influence of Diabetes On the Outcome of Acute Coronary Syndrome in Kuwait. Med Princ Pract. 2010;19(2):113-7. PubMed PMID: 20134173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of diabetes on the outcome of acute coronary syndrome in Kuwait. AU - Saad,Hisham, AU - Sawan,Sana, AU - Rashed,Wafa, AU - Zubaid,Mohammad, Y1 - 2010/02/04/ PY - 2009/02/08/received PY - 2009/05/24/accepted PY - 2010/2/6/entrez PY - 2010/2/6/pubmed PY - 2010/5/18/medline SP - 113 EP - 7 JF - Medical principles and practice : international journal of the Kuwait University, Health Science Centre JO - Med Princ Pract VL - 19 IS - 2 N2 - OBJECTIVES: To describe the baseline characteristics and management of patients with and without diabetes mellitus (DM) hospitalized with acute myocardial infarction (AMI) and to assess the influence of DM on hospital outcomes and hospital mortality. SUBJECTS AND METHODS: We analyzed data from a 6-month observational study (Kuwait Acute Coronary Syndrome Registry) of unselected patients admitted with a diagnosis of AMI over a period of 6 months, from December 2003 through May 2004. RESULTS: Of 1,295 patients enrolled, 609 (47%) were diabetics and 686 (53%) were non-diabetics. Diabetics were more likely to have a past history of coronary artery disease, hypertension and left ventricular systolic dysfunction than non-diabetics. There was less use of beta-blockers and aspirin in diabetics as compared to non-diabetics (62 vs. 71% and 95.5 vs. 97.9%, p < 0.03, for beta-blockers and aspirin, respectively). Left ventricular failure and cardiogenic shock occurred more often in diabetics compared to non-diabetics (16 vs. 7% and 5 vs. 3%, p < 0.001, for left ventricular failure and shock, respectively). The mortality rate was 6% for diabetics and 2% for non-diabetics (p < 0.001). CONCLUSION: DM is a major health problem among the adult population in Kuwait, and almost half the AMI population suffer from diabetes. Diabetic patients had higher rates of complications, especially left ventricular failure and cardiogenic shock, as compared to non-diabetic patients. The in-hospital mortality among diabetics with AMI was almost triple that of non-diabetics. The results of this study highlight the need to improve adherence to evidence-based treatment in diabetic patients with AMI. SN - 1423-0151 UR - https://www.unboundmedicine.com/medline/citation/20134173/Influence_of_diabetes_on_the_outcome_of_acute_coronary_syndrome_in_Kuwait_ L2 - https://www.karger.com?DOI=10.1159/000273070 DB - PRIME DP - Unbound Medicine ER -