Tags

Type your tag names separated by a space and hit enter

Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides.
Ann Nutr Metab 2010; 56(3):170-5AN

Abstract

BACKGROUND

Patients with highly increased plasma triglyceride levels are at risk of developing serious complications such as pancreatitis, coronary heart disease and stroke. Therefore it is important to rapidly decrease plasma triglyceride levels. A sufficient control of triglyceride levels with drugs like fibrates, statins or nicotinic acid can usually only be attained after a couple of weeks. Plasma exchange appears to be a fast but expensive method to reduce triglyceride levels. In this study we describe the use of a new omega-3 fatty acid and medium-chain triglyceride-rich formula diet as a therapeutic concept to reduce plasma triglyceride levels fast and effectively.

METHODS

Thirty-two patients with severe hypertriglyceridemia were treated with the especially composed formula diet for a period of 7 days.

RESULTS

Within this period of time, plasma triglycerides decreased from 1,601 (402-4,555) to 554 (142-2,382) mg/dl (p < 0.05). Total cholesterol levels were reduced from 417 (211-841) to 287 (165-457) mg/dl (p < 0.001). Fasting glucose and uric acid levels also slightly decreased (-8%; -12%). The formula diet as a 1-week treatment was well tolerated and accepted by the patients.

CONCLUSION

This diet was successfully used as an acute treatment in severe hypertriglyceridemia and showed effectiveness in rapidly and safely lowering plasma triglyceride levels.

Authors+Show Affiliations

Third Medical Department and Policlinic, University Hospital of Giessen and Marburg, Giessen, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20150726

Citation

Hauenschild, Annette, et al. "Successful Treatment of Severe Hypertriglyceridemia With a Formula Diet Rich in Omega-3 Fatty Acids and Medium-chain Triglycerides." Annals of Nutrition & Metabolism, vol. 56, no. 3, 2010, pp. 170-5.
Hauenschild A, Bretzel RG, Schnell-Kretschmer H, et al. Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides. Ann Nutr Metab. 2010;56(3):170-5.
Hauenschild, A., Bretzel, R. G., Schnell-Kretschmer, H., Kloer, H. U., Hardt, P. D., & Ewald, N. (2010). Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides. Annals of Nutrition & Metabolism, 56(3), pp. 170-5. doi:10.1159/000283561.
Hauenschild A, et al. Successful Treatment of Severe Hypertriglyceridemia With a Formula Diet Rich in Omega-3 Fatty Acids and Medium-chain Triglycerides. Ann Nutr Metab. 2010;56(3):170-5. PubMed PMID: 20150726.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides. AU - Hauenschild,Annette, AU - Bretzel,Reinhard G, AU - Schnell-Kretschmer,Henning, AU - Kloer,Hans-Ulrich, AU - Hardt,Philip D, AU - Ewald,Nils, Y1 - 2010/02/12/ PY - 2009/01/19/received PY - 2009/12/23/accepted PY - 2010/2/13/entrez PY - 2010/2/13/pubmed PY - 2010/7/14/medline SP - 170 EP - 5 JF - Annals of nutrition & metabolism JO - Ann. Nutr. Metab. VL - 56 IS - 3 N2 - BACKGROUND: Patients with highly increased plasma triglyceride levels are at risk of developing serious complications such as pancreatitis, coronary heart disease and stroke. Therefore it is important to rapidly decrease plasma triglyceride levels. A sufficient control of triglyceride levels with drugs like fibrates, statins or nicotinic acid can usually only be attained after a couple of weeks. Plasma exchange appears to be a fast but expensive method to reduce triglyceride levels. In this study we describe the use of a new omega-3 fatty acid and medium-chain triglyceride-rich formula diet as a therapeutic concept to reduce plasma triglyceride levels fast and effectively. METHODS: Thirty-two patients with severe hypertriglyceridemia were treated with the especially composed formula diet for a period of 7 days. RESULTS: Within this period of time, plasma triglycerides decreased from 1,601 (402-4,555) to 554 (142-2,382) mg/dl (p < 0.05). Total cholesterol levels were reduced from 417 (211-841) to 287 (165-457) mg/dl (p < 0.001). Fasting glucose and uric acid levels also slightly decreased (-8%; -12%). The formula diet as a 1-week treatment was well tolerated and accepted by the patients. CONCLUSION: This diet was successfully used as an acute treatment in severe hypertriglyceridemia and showed effectiveness in rapidly and safely lowering plasma triglyceride levels. SN - 1421-9697 UR - https://www.unboundmedicine.com/medline/citation/20150726/Successful_treatment_of_severe_hypertriglyceridemia_with_a_formula_diet_rich_in_omega_3_fatty_acids_and_medium_chain_triglycerides_ L2 - https://www.karger.com?DOI=10.1159/000283561 DB - PRIME DP - Unbound Medicine ER -