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Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts.
Chem Biodivers. 2010 Feb; 7(2):383-91.CB

Abstract

Panax notoginseng and Carthamus tinctorius are known as traditional medicinal plants, and they also have edible values. To better understand their pharmacological mechanism, the present study assessed the in vitro antioxidant activities of extracts of P. notoginseng (EPN) and C. tinctorius (ECT). In addition, the main components of EPN and ECT were determined by HPLC. The results show that EPN mainly contained saponins, which were effective in scavenging (.)OH and O(.)(2-), while showing a low activity in the DPPH(.) assay. Flavonoids were the main components of ECT and were active in scavenging all three radicals in a dose-dependent manner. In brief, the antioxidant properties of EPN and ECT are distinct and might be complementary, their combined use tending to be more effective in scavenging (.)OH (P<0.05 vs. EPN or ECT).

Authors+Show Affiliations

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20151384

Citation

Han, Shu-Yan, et al. "Component Analysis and Free Radical-scavenging Potential of Panax Notoginseng and Carthamus Tinctorius Extracts." Chemistry & Biodiversity, vol. 7, no. 2, 2010, pp. 383-91.
Han SY, Li HX, Bai CC, et al. Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts. Chem Biodivers. 2010;7(2):383-91.
Han, S. Y., Li, H. X., Bai, C. C., Wang, L., & Tu, P. F. (2010). Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts. Chemistry & Biodiversity, 7(2), 383-91. https://doi.org/10.1002/cbdv.200800313
Han SY, et al. Component Analysis and Free Radical-scavenging Potential of Panax Notoginseng and Carthamus Tinctorius Extracts. Chem Biodivers. 2010;7(2):383-91. PubMed PMID: 20151384.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts. AU - Han,Shu-Yan, AU - Li,Hai-Xia, AU - Bai,Chang-Cai, AU - Wang,Li, AU - Tu,Peng-Fei, PY - 2010/2/13/entrez PY - 2010/2/13/pubmed PY - 2010/5/19/medline SP - 383 EP - 91 JF - Chemistry & biodiversity JO - Chem Biodivers VL - 7 IS - 2 N2 - Panax notoginseng and Carthamus tinctorius are known as traditional medicinal plants, and they also have edible values. To better understand their pharmacological mechanism, the present study assessed the in vitro antioxidant activities of extracts of P. notoginseng (EPN) and C. tinctorius (ECT). In addition, the main components of EPN and ECT were determined by HPLC. The results show that EPN mainly contained saponins, which were effective in scavenging (.)OH and O(.)(2-), while showing a low activity in the DPPH(.) assay. Flavonoids were the main components of ECT and were active in scavenging all three radicals in a dose-dependent manner. In brief, the antioxidant properties of EPN and ECT are distinct and might be complementary, their combined use tending to be more effective in scavenging (.)OH (P<0.05 vs. EPN or ECT). SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/20151384/Component_analysis_and_free_radical_scavenging_potential_of_Panax_notoginseng_and_Carthamus_tinctorius_extracts_ L2 - https://doi.org/10.1002/cbdv.200800313 DB - PRIME DP - Unbound Medicine ER -