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[Surgical treatment of obstructive azoospermia: a report of 56 cases].
Zhonghua Nan Ke Xue. 2010 Jan; 16(1):48-51.ZN

Abstract

OBJECTIVE

To evaluate the diagnosis and surgical treatment of obstructive azoospermia.

METHODS

We analyzed the clinical data of 56 cases of obstructive azoospermia, 43 of them with ejaculatory duct obstruction (EDO), and the other 13 suspected of epididymal obstruction. The diagnostic methods included semen analyses, measurement of fructose and neutral alpha-glucosidase in the seminal plasma, transrectal ultrasonography (TRUS), and vasography when necessary. The 43 patients with EDO were treated by transurethral resection of the ejaculatory duct (TURED), and 11 of the 13 cases of suspected epididymal obstruction were confirmed by scrotal exploration and underwent either bilateral or unilateral vasoepididymostomy. The patients were followed up for 3 -51 months for postoperative semen quality and impregnation.

RESULTS

Of the 43 azoospermia patients with EDO treated by TURED, 36 (83.7%) showed improved semen parameters and 11 (25.6%) achieved pregnancies. Among the 11 cases of azoospermia with confirmed epididymal obstruction treated by vasoepididymostomy, 6 (54.5%) had sperm in the semen assay and 3 (27.3%) achieved pregnancies.

CONCLUSION

Semen analyses, measurement of fructose and neutral alpha-glucosidase in the seminal plasma, TRUS and vasography are important diagnostic methods for obstructive azoospermia. TURED is effective for azoospermia with EDO, while vasoepididymostomy is preferable for the treatment of azoospermia with epididymal obstruction.

Authors+Show Affiliations

Tu XA
Department of Urology, Huangpu Branch of the First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510700, China.
Zhao LY
No affiliation info available
Deng LW
No affiliation info available
Wang WW
No affiliation info available
Zhao L
No affiliation info available
Liang H
No affiliation info available
Zeng LY
No affiliation info available
Deng CH
No affiliation info available

MeSH

AdultAzoospermiaEpididymisHumansMaleRadiographyRectumTreatment OutcomeUltrasonographyVas Deferens

Pub Type(s)

Journal Article

Language

chi

PubMed ID

20180405

Citation

Tu, Xiang-An, et al. "[Surgical Treatment of Obstructive Azoospermia: a Report of 56 Cases]." Zhonghua Nan Ke Xue = National Journal of Andrology, vol. 16, no. 1, 2010, pp. 48-51.
Tu XA, Zhao LY, Deng LW, et al. [Surgical treatment of obstructive azoospermia: a report of 56 cases]. Zhonghua Nan Ke Xue. 2010;16(1):48-51.
Tu, X. A., Zhao, L. Y., Deng, L. W., Wang, W. W., Zhao, L., Liang, H., Zeng, L. Y., & Deng, C. H. (2010). [Surgical treatment of obstructive azoospermia: a report of 56 cases]. Zhonghua Nan Ke Xue = National Journal of Andrology, 16(1), 48-51.
Tu XA, et al. [Surgical Treatment of Obstructive Azoospermia: a Report of 56 Cases]. Zhonghua Nan Ke Xue. 2010;16(1):48-51. PubMed PMID: 20180405.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Surgical treatment of obstructive azoospermia: a report of 56 cases]. AU - Tu,Xiang-An, AU - Zhao,Liang-Yun, AU - Deng,Li-Wen, AU - Wang,Wen-Wei, AU - Zhao,Liang, AU - Liang,Hui, AU - Zeng,Ling-You, AU - Deng,Chun-Hua, PY - 2010/2/26/entrez PY - 2010/2/26/pubmed PY - 2010/5/14/medline SP - 48 EP - 51 JF - Zhonghua nan ke xue = National journal of andrology JO - Zhonghua Nan Ke Xue VL - 16 IS - 1 N2 - OBJECTIVE: To evaluate the diagnosis and surgical treatment of obstructive azoospermia. METHODS: We analyzed the clinical data of 56 cases of obstructive azoospermia, 43 of them with ejaculatory duct obstruction (EDO), and the other 13 suspected of epididymal obstruction. The diagnostic methods included semen analyses, measurement of fructose and neutral alpha-glucosidase in the seminal plasma, transrectal ultrasonography (TRUS), and vasography when necessary. The 43 patients with EDO were treated by transurethral resection of the ejaculatory duct (TURED), and 11 of the 13 cases of suspected epididymal obstruction were confirmed by scrotal exploration and underwent either bilateral or unilateral vasoepididymostomy. The patients were followed up for 3 -51 months for postoperative semen quality and impregnation. RESULTS: Of the 43 azoospermia patients with EDO treated by TURED, 36 (83.7%) showed improved semen parameters and 11 (25.6%) achieved pregnancies. Among the 11 cases of azoospermia with confirmed epididymal obstruction treated by vasoepididymostomy, 6 (54.5%) had sperm in the semen assay and 3 (27.3%) achieved pregnancies. CONCLUSION: Semen analyses, measurement of fructose and neutral alpha-glucosidase in the seminal plasma, TRUS and vasography are important diagnostic methods for obstructive azoospermia. TURED is effective for azoospermia with EDO, while vasoepididymostomy is preferable for the treatment of azoospermia with epididymal obstruction. SN - 1009-3591 UR - https://www.unboundmedicine.com/medline/citation/20180405/[Surgical_treatment_of_obstructive_azoospermia:_a_report_of_56_cases]_ DB - PRIME DP - Unbound Medicine ER -