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Caffeine, diabetes, cognition, and dementia.
J Alzheimers Dis. 2010; 20 Suppl 1:S143-50.JA

Abstract

People with diabetes mellitus are at increased risk of cognitive dysfunction. This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM). Epidemiological studies on caffeine/coffee intake and T2DM risk are reviewed. Next, the impact of T2DM on cognition is addressed. Finally, the potential for caffeine to modulate the risk of cognitive decline in the context of diabetes is explored. The conclusion is that, although epidemiological studies indicate that coffee/caffeine consumption is associated with a decreased risk of T2DM and possibly also with a decreased dementia risk, we can at present not be certain that these associations are causal. For now, recommendations for coffee consumption in individuals with T2DM or pre-diabetic stages are therefore difficult to establish, but it should be acknowledged that caffeine does appear to have several properties that warrant further investigations in this field.

Authors+Show Affiliations

Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands. g.j.biessels@umcutrecht.nl

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20182038

Citation

Biessels, Geert Jan. "Caffeine, Diabetes, Cognition, and Dementia." Journal of Alzheimer's Disease : JAD, vol. 20 Suppl 1, 2010, pp. S143-50.
Biessels GJ. Caffeine, diabetes, cognition, and dementia. J Alzheimers Dis. 2010;20 Suppl 1:S143-50.
Biessels, G. J. (2010). Caffeine, diabetes, cognition, and dementia. Journal of Alzheimer's Disease : JAD, 20 Suppl 1, S143-50. https://doi.org/10.3233/JAD-2010-091228
Biessels GJ. Caffeine, Diabetes, Cognition, and Dementia. J Alzheimers Dis. 2010;20 Suppl 1:S143-50. PubMed PMID: 20182038.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Caffeine, diabetes, cognition, and dementia. A1 - Biessels,Geert Jan, PY - 2010/2/26/entrez PY - 2010/2/26/pubmed PY - 2010/9/3/medline SP - S143 EP - 50 JF - Journal of Alzheimer's disease : JAD JO - J Alzheimers Dis VL - 20 Suppl 1 N2 - People with diabetes mellitus are at increased risk of cognitive dysfunction. This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM). Epidemiological studies on caffeine/coffee intake and T2DM risk are reviewed. Next, the impact of T2DM on cognition is addressed. Finally, the potential for caffeine to modulate the risk of cognitive decline in the context of diabetes is explored. The conclusion is that, although epidemiological studies indicate that coffee/caffeine consumption is associated with a decreased risk of T2DM and possibly also with a decreased dementia risk, we can at present not be certain that these associations are causal. For now, recommendations for coffee consumption in individuals with T2DM or pre-diabetic stages are therefore difficult to establish, but it should be acknowledged that caffeine does appear to have several properties that warrant further investigations in this field. SN - 1875-8908 UR - https://www.unboundmedicine.com/medline/citation/20182038/Caffeine_diabetes_cognition_and_dementia_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -